Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422954 | 0.87 | ALDH1A1 (0.49) | PARP1LCKBRD4KDM4EALDH1A1 | |
| SCHEMBL3359193 | 0.87 | MKNK1 (0.46) | PARP1MKNK1MKNK2SIRT3TDP1 | |
| SCHEMBL1757694 | 0.87 | GRM1 (0.53) | MKNK1MKNK2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8150009 | 0.85 | PRSS1 (0.64) | MKNK1MKNK2SIRT3TDP1PRSS1 | |
| SCHEMBL6825758 | 0.84 | PARP1 (0.50) | PARP1LCKBRD4KDM4EALDH1A1 | |
| SCHEMBL1002832 | 0.84 | PRSS1 (0.61) | PARP1LCKALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL29503140 | 0.84 | PRSS1 (0.61) | PARP1LCKALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL5679029 | 0.84 | PARP1 (0.50) | PARP1MKNK1MKNK2ALDH1A1SMN1; SMN2 | |
| Acetic Acid SCHEMBL28636109 | 0.84 | MKNK1 (0.44) | MKNK1MKNK2SMN1; SMN2SIRT3TDP1 | |
| SCHEMBL23528922 | 0.82 | KDM4E (0.56) | PARP1KDM4EALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114413-A | POLYAMIDE RESIN COMPOSITION AND MOLDED ARTICLE PRODUCED THEREFROM | 乐天尖端材料株式会社 | 2019-08-09 | — | — | CN | claimed |
| CN-109476910-A | Conductive thermoplastic polyamide molding material | EMS 专利股份公司 | 2019-03-15 | — | — | CN | claimed |
| CN-106939125-A | Fire-retardant partially aromatic polyamide moulding masses | EMS 专利股份公司 | 2017-07-11 | — | — | CN | claimed |
| US-8012956-B2 | Tropane compounds | EXELIXIS, INC. (US) | 2011-09-06 | — | — | US | claimed |
| JP-2009544611-A | — | — | 2009-12-17 | — | — | JP | claimed |
| US-20090163471-A1 | Tropane compounds | EXELIXIS, INC. | 2009-06-25 | — | — | US | claimed |
| EP-2049124-A2 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | Merck & Co., Inc. (US) | 2009-04-22 | — | — | EP | claimed |
| WO-2008010985-A2 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | MERCK & CO., INC. (US) | 2008-01-24 | — | — | WO | claimed |
| EP-1769094-A2 | SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOAMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS | Reaxa Limited (GB) | 2007-04-04 | — | — | EP | claimed |
| WO-2005123971-A2 | SCAVENGER SUPPORTS WITH AMINO-FUNCTIONALISED PENDANT KETOESTER OR KETOMIDE GROUPS FOR REMOVING METALS FROM SOLUTIONS | REAXA LIMITED (GB) | 2005-12-29 | — | — | WO | claimed |
| US-20260049077-A1 | Neurotrophic Receptor Tyrosine Kinase (NTRK) Inhibitors and Methods Using Same | BAYLOR COLLEGE MEDICINE (US) | 2026-02-19 | — | — | US | disclosed |
| CN-119947875-A | Method for producing glass fiber reinforced polyamide resin composition | 菱环球聚甲醛株式会社 | 2025-05-06 | — | — | CN | disclosed |
| US-20240424113-A1 | CONJUGATES COMPRISING ANTIFUNGALS AND HEAT SHOCK PROTEIN 90 (HSP90) INHIBITORS AND METHODS OF USE THEREOF | BRIGHT ANGEL THERAPEUTICS INC. (CA) | 2024-12-26 | — | — | US | disclosed |
| CN-119100970-A | Bivalent inhibitor based on heat shock protein 90 and preparation method and application thereof | 中国药科大学 | 2024-12-10 | — | — | CN | disclosed |
| US-20240279338-A1 | Combination Treatment of Cancer | ARES TRADING SA (CH) | 2024-08-22 | — | — | US | disclosed |
| WO-2006028958-A2 | PYRIDYL INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| US-20040116399-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-17 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |
| US-4259258-A | Preparation of bis-n-chloramides of cycloaliphatic carboxylic acids | AKZONA INCORPORATED (US) | 1981-03-31 | — | — | US | disclosed |
| US-4053510-A | REACTING A DICARBOXYLIC ACID WITH UREA IN CHLOROSULFONIC ACID OR OLEUM | AKZO N.V. (NL) | 1977-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279338-A1 | Combination Treatment of Cancer | CD274, PDCD1, ENTPD1 | PARP1 22/4885MKNK1 1360/4885MKNK2 2094/4885 |
| US-20090163471-A1 | Tropane compounds | ADRA1B, ADRA2B, ADRB2 | PARP1 3161/4885MKNK1 4784/4885MKNK2 4524/4885 |
| US-20260049077-A1 | Neurotrophic Receptor Tyrosine Kinase (NTRK) Inhibitors and Methods Using Same | NTRK2, NTRK3, NTRK1 | PARP1 1922/4885MKNK1 1549/4885MKNK2 1368/4885 |
| US-20240424113-A1 | CONJUGATES COMPRISING ANTIFUNGALS AND HEAT SHOCK PROTEIN 90 (HSP90) INHIBITORS AND METHODS OF USE THEREOF | HSP90AB1, HSP90B1, HSP90AA1 | PARP1 4123/4885MKNK1 514/4885MKNK2 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.