SCHEMBL17691900

SCHEMBL17691900

c1ccc(-c2ccnc(-c3ccc4c(ccc5cc(-c6cc(-c7ccccn7)ccn6)ccc54)c3)c2)nc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.44
LMNA P02545 3/20 0.44
TP53 P04637 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.44
TSHR P16473 1/20 0.44
KLF5 Q13887 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PIK3CD O00329 1/20 0.44
PIK3CA P42336 1/20 0.44
PI4KA P42356 1/20 0.44
PIK3CG P48736 1/20 0.44
PI4KB Q9UBF8 1/20 0.44
CCR1 P32246 3/20 0.43
CCR5 P51681 3/20 0.43
CCR8 P51685 3/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17691840 0.93 KDM4E (0.50) KDM4ELMNATP53SMN1; SMN2ALDH1A1
SCHEMBL12277737 0.91 KDM4E (0.48) KDM4ELMNATP53SMN1; SMN2ALDH1A1
SCHEMBL4242609 0.88 KDM4E (0.49) KDM4ELMNATP53SMN1; SMN2ALDH1A1
SCHEMBL17692070 0.86 LMNA (0.50) KDM4ELMNATP53SMN1; SMN2ALDH1A1
SCHEMBL17691894 0.86 ASIC3 (0.44) PIK3CACYP1A2MAPKAPK2
SCHEMBL17692012 0.84 TGFBR1 (0.38) KDM4ELMNATP53SMN1; SMN2ALDH1A1
SCHEMBL17229040 0.84 PRMT5 (0.46) KDM4ELMNAALDH1A1PIK3CDPIK3CA
SCHEMBL17427678 0.84 PRMT5 (0.46) KDM4ELMNAALDH1A1PIK3CDPIK3CA
SCHEMBL26260190 0.83 KDM4E (0.57) KDM4ELMNATP53SMN1; SMN2ALDH1A1
SCHEMBL10031174 0.83 CCR1 (0.53) KDM4ELMNATP53SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed