SCHEMBL17692265

SCHEMBL17692265

c1ccc(-c2ccc3c4c(cccc24)-c2ccccc2-3)c(-c2ccc3sc4ccccc4c3c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.46
GPR3 P46089 1/20 0.44
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
ALDH1A1 P00352 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
HPGD P15428 2/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
MAPT P10636 5/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17692252 0.95 ALOX5 (0.47) ALOX5GPR3CRHBPCRHR2KEAP1
SCHEMBL24735511 0.92 CRHBP (0.43) ALOX5GPR3CRHBPCRHR2KEAP1
SCHEMBL27302591 0.90 ALOX5 (0.38) ALOX5GPR3CRHBPCRHR2KEAP1
SCHEMBL17692261 0.89 GPR3 (0.42) ALOX5GPR3CRHBPCRHR2KEAP1
SCHEMBL17692260 0.88 ALOX5 (0.42) ALOX5GPR3CRHBPCRHR2KEAP1
SCHEMBL18820576 0.87 MAPT (0.40) ALOX5GPR3CRHBPCRHR2KEAP1
SCHEMBL22881816 0.87 GPR3 (0.40) ALOX5GPR3CRHBPCRHR2KEAP1
SCHEMBL21283018 0.87 GPR3 (0.58) ALOX5GPR3ALDH1A1L3MBTL1HPGD
SCHEMBL18820533 0.86 CRHBP (0.39) ALOX5GPR3CRHBPCRHR2KEAP1
SCHEMBL14733787 0.85 GPR3 (0.52) ALOX5GPR3ALDH1A1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed