Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | Q9HBH1 | 1/20 | 0.31 | |
| ▸ | MMP2 | P08253 | 5/20 | 0.31 |
| ▸ | MMP3 | P08254 | 5/20 | 0.31 |
| ▸ | MMP1 | P03956 | 4/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919170 | 1.00 | CA2 (0.41) | CA2CTSCCYP1A2CYP3A4RECQL | |
| SCHEMBL2081935 | 1.00 | CA2 (0.41) | CA2CTSCCYP1A2CYP3A4RECQL | |
| Trifluoroacetic Acid SCHEMBL918802 | 0.91 | CA2 (0.37) | CA2CTSCMMP13 | |
| SCHEMBL7765975 | 0.83 | CTSC (0.32) | CTSCCYP1A2CYP3A4RECQLPDF | |
| SCHEMBL8374072 | 0.80 | CTSC (0.32) | CTSCPDF | |
| SCHEMBL27542499 | 0.80 | MMP2 (0.43) | CA2CYP3A4ALDH1A1MAPTMMP2 | |
| SCHEMBL27542496 | 0.80 | MMP2 (0.43) | CA2CYP3A4ALDH1A1MAPTMMP2 | |
| SCHEMBL2909005 | 0.79 | CA2 (0.38) | CA2ALDH1A1MMP2MMP3MMP1 | |
| SCHEMBL15623787 | 0.79 | FAAH (0.42) | CA2RECQLMAPK1ALDH1A1MMP13 | |
| SCHEMBL13449084 | 0.79 | HPGD (0.40) | CA2CYP1A2CYP3A4MAPTPDF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103483419-B | A kind of Telaprevir intermediate C crystal form and synthetic method thereof | SUZHOU UUGENE BIOPHARMA CO., LTD. (CN) | 2015-09-09 | — | — | CN | disclosed |
| CN-103483419-A | Telaprevir intermediate in crystal form C, and synthesis method thereof | SUZHOU UUGENE BIOPHARMA CO LTD | 2014-01-01 | — | — | CN | disclosed |
| WO-2011060832-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |