SCHEMBL1769475

SCHEMBL1769475

CCCCCC(CC)C(CCCC)C(=O)OCC

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.42
CA1 P00915 3/20 0.42
ZDHHC7 Q9NXF8 1/20 0.40
TSHR P16473 2/20 0.38
CYP3A4 P08684 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPK1 P28482 1/20 0.37
GPR84 Q9NQS5 3/20 0.36
FFAR1 O14842 1/20 0.36
CPB2 Q96IY4 1/20 0.36
MAPT P10636 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2117996 0.91 ZDHHC7 (0.44) CA2CA1ZDHHC7GPR84FFAR1
SCHEMBL21694542 0.89 CA2 (0.42) CA2CA1ZDHHC7TSHRCYP3A4
SCHEMBL27653256 0.86 NAAA (0.46) CA2CA1ZDHHC7TSHRMAPT
SCHEMBL28286148 0.85 ZDHHC7 (0.37) CA2CA1ZDHHC7TSHRCYP3A4
SCHEMBL13269368 0.85 ZDHHC7 (0.47) CA2CA1ZDHHC7GPR84FFAR1
SCHEMBL28919681 0.84 NAAA (0.47) ZDHHC7TSHRMAPT
SCHEMBL28139049 0.83 CA2 (0.40) CA2CA1TSHRCYP3A4ATM
SCHEMBL7070785 0.83 ZDHHC7 (0.50) CA2ZDHHC7GPR84FFAR1CPB2
SCHEMBL19690704 0.83 ZDHHC7 (0.50) CA2ZDHHC7GPR84FFAR1CPB2
SCHEMBL234311 0.82 CA2 (0.47) CA2CA1ZDHHC7TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10946101-B2 Surfactant-free water-free foamable compositions, breakable foams and gels and their uses VYNE THERAPEUTICS INC. (US) 2021-03-16 US claimed
US-20210015927-A1 SURFACTANT-FREE WATER-FREE FOAMABLE COMPOSITIONS, BREAKABLE FOAMS AND GELS AND THEIR USES SWK FUNDING LLC 2021-01-21 US claimed
US-20190134204-A1 SURFACTANT-FREE WATER-FREE FOAMABLE COMPOSITIONS, BREAKABLE FOAMS AND GELS AND THEIR USES SWK FUNDING LLC 2019-05-09 US claimed
US-10137200-B2 Surfactant-free water-free foamable compositions, breakable foams and gels and their uses FOAMIX PHARMACEUTICALS LTD. (IL) 2018-11-27 US claimed
US-20180193469-A1 SURFACTANT-FREE WATER-FREE FOAMABLE COMPOSITIONS, BREAKABLE FOAMS AND GELS AND THEIR USES FOAMIX PHARMACEUTICALS LTD. (IL) 2018-07-12 US claimed
US-8945516-B2 Surfactant-free water-free foamable compositions, breakable foams and gels and their uses FOAMIX PHARMACEUTICALS LTD. (IL) 2015-02-03 US claimed
US-20070154439-A1 Cosmetic composition for use around the eyes DORF PAULA 2007-07-05 US claimed
CN-115531250-B Sustained-release cosmetic composition with grid structure and lasting dynamic oil control balance 上海永熙信息科技有限公司 2023-09-12 CN disclosed
CN-116602891-A Breathable oil-water balanced skin-nourishing plant soft film cosmetic composition before makeup 上海永熙信息科技有限公司 2023-08-18 CN disclosed
CN-115531250-A Dynamic oil control balance lasting slow-release cosmetic composition with grid structure 上海永熙信息科技有限公司 2022-12-30 CN disclosed
CN-114980895-A Metered dose for demodex and related disorders 阿祖拉眼科有限公司 2022-08-30 CN disclosed
CN-114980957-A Metered dose for intraocular or periocular disorders 阿祖拉眼科有限公司 2022-08-30 CN disclosed
US-10653610-B2 Essentially anhydrous hair-treatment compositions comprising a bis-urea derivative and silica aerogel L'OREAL (FR) 2020-05-19 US disclosed
CN-104168873-A Colour changing composition OREAL 2014-11-26 CN disclosed
CN-104168870-A Color changing composition in gel form OREAL 2014-11-26 CN disclosed
CN-104168874-A Color-changing composition with polyol OREAL 2014-11-26 CN disclosed
CN-104168959-A Color-changing composition with UV filter OREAL 2014-11-26 CN disclosed
CN-104168871-A Changing-color composition in foam form OREAL 2014-11-26 CN disclosed
WO-2011061672-A1 MIXTURE OF HYDROCARBON SOLVENTS L'OREAL (FR) 2011-05-26 WO disclosed
CN-101702880-A Highly stable electrolyzed water with reduced NMR half-value width AKUATECH S R L 2010-05-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10653610-B2 Essentially anhydrous hair-treatment compositions comprising a bis-urea derivative and silica aerogel FHIT, SUCLG1, SHH CA2 2379/4885CA1 1581/4885ZDHHC7 2786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.