Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17694847 | 1.00 | TBK1 (0.33) | TBK1 | |
| SCHEMBL17694838 | 0.90 | CTSS (0.35) | — | |
| SCHEMBL17694844 | 0.86 | TBK1 (0.39) | TBK1 | |
| SCHEMBL17694845 | 0.82 | TBK1 (0.34) | TBK1 | |
| SCHEMBL15337482 | 0.80 | ULK1 (0.40) | TBK1 | |
| SCHEMBL15337651 | 0.80 | ULK1 (0.40) | TBK1 | |
| SCHEMBL15337710 | 0.80 | ULK1 (0.40) | TBK1 | |
| SCHEMBL19527806 | 0.80 | ULK1 (0.40) | TBK1 | |
| SCHEMBL19836220 | 0.74 | TBK1 (0.41) | TBK1 | |
| SCHEMBL19836242 | 0.74 | TBK1 (0.41) | TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2833889-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2017-11-01 | — | — | EP | claimed |
| US-9321763-B2 | Protein kinase C inhibitors and uses thereof | RIGEL PHARMACEUTICALS, INC. (US) | 2016-04-26 | — | — | US | claimed |