Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30138611 | 0.90 | TSHR (0.56) | TSHRALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL18923939 | 0.87 | TSHR (0.62) | TSHRALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL10044367 | 0.87 | TSHR (0.85) | TSHRALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL21821634 | 0.86 | TSHR (0.84) | TSHRALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL12733524 | 0.85 | TSHR (0.76) | TSHRALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL16589858 | 0.85 | TSHR (0.69) | TSHRALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL19370866 | 0.85 | TSHR (0.75) | TSHRALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL26297954 | 0.83 | ALDH1A1 (0.53) | TSHRALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL12686632 | 0.83 | ALDH1A1 (0.62) | TSHRALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL15849202 | 0.83 | ALDH1A1 (0.62) | TSHRALDH1A1KDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |
| WO-2011060832-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVITY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |