Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12686632 | 0.96 | ALDH1A1 (0.62) | TSHRALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL15849202 | 0.96 | ALDH1A1 (0.62) | TSHRALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL17369037 | 0.92 | TSHR (0.61) | TSHRALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL12733524 | 0.91 | TSHR (0.76) | TSHRALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL16589858 | 0.91 | TSHR (0.69) | TSHRALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL18923980 | 0.91 | TSHR (0.56) | TSHRALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL18923938 | 0.91 | TSHR (0.56) | TSHRALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL1769656 | 0.87 | TSHR (0.63) | TSHRALDH1A1HPGDEPHX2KDM4E | |
| SCHEMBL12673953 | 0.87 | ALDH1A1 (0.55) | TSHRALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL11921661 | 0.87 | ALDH1A1 (0.55) | TSHRALDH1A1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670261-B2 | Functionalized exendin-4 derivatives | SANOFI (FR) | 2017-06-06 | — | — | US | disclosed |