Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10596455 | 1.00 | CHRM3 (0.51) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL4146916 | 1.00 | CHRM3 (0.51) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL4138872 | 0.93 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL4153935 | 0.87 | CHRM3 (0.55) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL7643094 | 0.85 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL18248596 | 0.85 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL28118919 | 0.85 | CHRM2 (0.40) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL18248486 | 0.85 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL17749475 | 0.84 | CHRM3 (0.53) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL10607860 | 0.84 | KCNH2 (0.38) | CHRM3CHRM2KCNH2LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061545-A1 | HPLC METHOD FOR ANALYZING VORINOSTAT | GENERICS [UK] LIMITED (GB) | 2011-05-26 | — | — | WO | claimed |
| CN-103018347-B | High-performance liquid chromatography analysis method for impurities in vorinostat and drug composition thereof | BEIJING BENCAO TIANYUAN PHARMACEUTICAL RES INST | 2015-07-15 | — | — | CN | disclosed |
| CN-103018346-A | High-performance liquid chromatography analysis method for impurities in vorinostat and drug composition thereof | BEIJING BENCAO TIANYUAN PHARMACEUTICAL RES INST | 2013-04-03 | — | — | CN | disclosed |
| CN-103018347-A | High-performance liquid chromatography analysis method for impurities in vorinostat and drug composition thereof | BEIJING BENCAO TIANYUAN PHARMACEUTICAL RES INST | 2013-04-03 | — | — | CN | disclosed |
| EP-1260529-A1 | Propylene polymers with improved properties | Borealis Technology OY (FI) | 2002-11-27 | — | — | EP | disclosed |