Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1769745 | 1.00 | CHRM3 (0.51) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL10596455 | 1.00 | CHRM3 (0.51) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL4138872 | 0.93 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL4153935 | 0.87 | CHRM3 (0.55) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL7643094 | 0.85 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL18248596 | 0.85 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL28118919 | 0.85 | CHRM2 (0.40) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL18248486 | 0.85 | CHRM3 (0.54) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL17749475 | 0.84 | CHRM3 (0.53) | CHRM3CHRM2KCNH2LMNACYP2D6 | |
| SCHEMBL10607860 | 0.84 | KCNH2 (0.38) | CHRM3CHRM2KCNH2LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | BASF SE (DE) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | PRMT5, CYC1, CBR3 | CHRM3 797/4885CHRM2 695/4885KCNH2 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.