Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.35 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177197 | 0.84 | ALDH1A1 (0.39) | HPGDALDH1A1KDM4EGAAALPL | |
| SCHEMBL177327 | 0.73 | RORC (0.36) | RORC | |
| SCHEMBL26646852 | 0.73 | RORC (0.31) | RORC | |
| SCHEMBL26646849 | 0.73 | RORC (0.31) | RORC | |
| SCHEMBL9952327 | 0.69 | ELANE (0.45) | KDM4ERORC | |
| SCHEMBL4660529 | 0.69 | ELANE (0.44) | ALDH1A1RORCSMN1; SMN2MAPT | |
| SCHEMBL14738967 | 0.68 | CPT1A (0.36) | HPGDALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL15578607 | 0.68 | ALDH1A1 (0.45) | HPGDALDH1A1KDM4EGAARORC | |
| SCHEMBL15578604 | 0.68 | DYRK1A (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14738410 | 0.67 | CA12 (0.41) | HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |