Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407512 | 0.88 | LYPLA1 (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4NPY5R | |
| SCHEMBL17698471 | 0.79 | HTR1D (0.38) | NPY5RCA1CA2NPY2RLTA4H | |
| SCHEMBL3275764 | 0.78 | NPY5R (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4NPY5R | |
| SCHEMBL1206432 | 0.66 | KDM4E (0.52) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL1205734 | 0.66 | KDM4E (0.52) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL817422 | 0.66 | KDM4E (0.52) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL9995387 | 0.63 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL12071516 | 0.63 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL5398515 | 0.63 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E | |
| SCHEMBL28144242 | 0.63 | CHRNB2 (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961756-B1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-04-27 | — | — | EP | claimed |
| EP-1961756-B1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-04-27 | — | — | EP | disclosed |