Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYPLA1 | O75608 | 1/20 | 0.46 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17698452 | 0.88 | CHRNB2 (0.40) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12266297 | 0.77 | LYPLA1 (0.65) | LYPLA1LYPLA2LTA4HCYP1A2TSHR | |
| SCHEMBL13476023 | 0.76 | LYPLA1 (0.63) | LYPLA1LYPLA2LTA4HSLC6A2SLC6A4 | |
| SCHEMBL2404635 | 0.73 | HTR1D (0.32) | LYPLA1LYPLA2SLC6A4CYP1A2TSHR | |
| SCHEMBL13476042 | 0.71 | LYPLA1 (0.63) | LYPLA1LYPLA2LTA4HCHRM1OPRM1 | |
| SCHEMBL17698471 | 0.69 | HTR1D (0.38) | LTA4HNPY5RALDH1A1 | |
| SCHEMBL3275764 | 0.69 | NPY5R (0.41) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12266287 | 0.68 | LYPLA1 (0.70) | LYPLA1LYPLA2LTA4HCHRM1OPRM1 | |
| SCHEMBL14135146 | 0.68 | LYPLA1 (0.62) | LYPLA1LYPLA2LTA4HCHRM1OPRM1 | |
| SCHEMBL12270616 | 0.68 | LYPLA1 (0.73) | LYPLA1LYPLA2LTA4HCYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961756-B1 | NOVEL BISBORON COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2016-04-27 | — | — | EP | claimed |
| US-8853424-B2 | Protein cross-linking inhibitor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | BAZ2B, PRMT1, BRIX1 | LYPLA1 1153/4885LYPLA2 1988/4885LTA4H 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.