Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29565964 | 0.83 | IDO1 (0.33) | MEN1KMT2AMAPTTDP1HSD17B10 | |
| SCHEMBL29912733 | 0.83 | IDO1 (0.33) | MEN1KMT2AMAPTTDP1HSD17B10 | |
| SCHEMBL1133892 | 0.83 | IDO1 (0.33) | MEN1KMT2AMAPTTDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL498746 | 0.82 | GAA (0.33) | MEN1KMT2AMAPTTDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL20994607 | 0.82 | GAA (0.33) | MEN1KMT2AMAPTTDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL29920895 | 0.71 | KDM4E (0.31) | MAPTTDP1HSD17B10ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6806923 | 0.71 | KDM4E (0.31) | MAPTTDP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL972682 | 0.68 | SNCA (0.46) | MEN1KMT2AMAPTTDP1HSD17B10 | |
| SCHEMBL7209663 | 0.66 | MAPT (0.33) | MEN1KMT2AMAPTTDP1NPC1 | |
| Iodide SCHEMBL3711622 | 0.66 | NOX1 (0.55) | MEN1KMT2AMAPTTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795491-B2 | Photoactivatable antimicrobial agents and therapeutic and diagnostic methods of using same | THE GENERAL HOSPITAL CORPORATION (US) | 2023-10-24 | — | — | US | disclosed |
| EP-3056497-B1 | METHODS USING BODIPY-LABELLED ENZYME SUBSTRATES | MASSACHUSETTS GEN HOSPITAL (US) | 2018-08-29 | — | — | EP | disclosed |
| US-20180094292-A1 | Photoactivatable Antimicrobial Agents And Therapeutic And Diagnostic Methods Of Using Same | THE GENERAL HOSPITAL CORPORATION | 2018-04-05 | — | — | US | disclosed |
| US-9828622-B2 | Photoactivatable antimicrobial agents and therapeutic and diagnostic methods of using same | THE GENERAL HOSPITAL CORPORATION (US) | 2017-11-28 | — | — | US | disclosed |
| EP-3056497-A1 | BODIPY-LABELLED ENZYME SUBSTRATES AND METHODS USING THEM | The General Hospital Corporation (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2285381-B1 | PHOTOACTIVATABLE BETA-LACTAMASE SUBSTRATES AND ANALYTICAL METHODS OF USING SAME | GEN HOSPITAL CORP (US) | 2015-12-16 | — | — | EP | disclosed |
| US-20110112059-A1 | PHOTOACTIVATABLE ANTIMICROBIAL AGENTS AND THERAPEUTIC AND DIAGNOSTIC METHODS OF USING SAME | THE GENERAL HOSPITAL CORPORATION (US) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180094292-A1 | Photoactivatable Antimicrobial Agents And Therapeutic And Diagnostic Methods Of Using Same | HMBS, GUSB, LCT | MEN1 2963/4885KMT2A 1703/4885MAPT 2958/4885 |
| US-11795491-B2 | Photoactivatable antimicrobial agents and therapeutic and diagnostic methods of using same | HMBS, GUSB, LCT | MEN1 2963/4885KMT2A 1703/4885MAPT 2958/4885 |
| US-20110112059-A1 | PHOTOACTIVATABLE ANTIMICROBIAL AGENTS AND THERAPEUTIC AND DIAGNOSTIC METHODS OF USING SAME | HMBS, GUSB, LCT | MEN1 2963/4885KMT2A 1703/4885MAPT 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.