Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29920895 | 1.00 | KDM4E (0.31) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL31086299 | 0.99 | SNCA (0.31) | SNCA | |
| Hydrochloric Acid SCHEMBL20994607 | 0.87 | GAA (0.33) | KDM4EALDH1A1LMNATP53GAA | |
| Hydrochloric Acid SCHEMBL498746 | 0.87 | GAA (0.33) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL1133892 | 0.86 | IDO1 (0.33) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL29912733 | 0.86 | IDO1 (0.33) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL29565964 | 0.86 | IDO1 (0.33) | KDM4EALDH1A1LMNATP53GAA | |
| Hydrochloric Acid SCHEMBL7760385 | 0.72 | MEN1 (0.36) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL972682 | 0.71 | SNCA (0.46) | KDM4EALDH1A1LMNATP53GAA | |
| Hydrochloric Acid SCHEMBL8570840 | 0.71 | TERT (0.31) | KDM4EALDH1A1LMNATP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12318451-B2 | Method for inducing tumor regression | VEROSCIENCE LLC (US) | 2025-06-03 | — | — | US | claimed |
| US-20230263892-A1 | METHOD FOR INDUCING TUMOR REGRESSION | VEROSCIENCE LLC | 2023-08-24 | — | — | US | claimed |
| US-20040102383-A1 | Growth inhibition and eradication of solid tumors using neuroendocrine resetting therapy and photodynamic therapy | CINCOTTA ANTHONY H (US) | 2004-05-27 | — | — | US | claimed |
| US-20250269029-A1 | METHOD FOR INDUCING TUMOR REGRESSION | VEROSCIENCE LLC | 2025-08-28 | — | — | US | disclosed |
| US-12357693-B2 | Method for inducing tumor regression | VEROSCIENCE LLC (US) | 2025-07-15 | — | — | US | disclosed |
| US-12318451-B2 | Method for inducing tumor regression | VEROSCIENCE LLC (US) | 2025-06-03 | — | — | US | disclosed |
| US-20230263892-A1 | METHOD FOR INDUCING TUMOR REGRESSION | VEROSCIENCE LLC | 2023-08-24 | — | — | US | disclosed |
| US-11607455-B2 | Method for inducing tumor regression | VEROSCIENCE LLC (US) | 2023-03-21 | — | — | US | disclosed |
| US-20220288209-A1 | METHOD FOR INDUCING TUMOR REGRESSION | VEROSCIENCE LLC | 2022-09-15 | — | — | US | disclosed |
| EP-4034128-A1 | METHOD FOR INDUCING TUMOR REGRESSION | VeroScience LLC (US) | 2022-08-03 | — | — | EP | disclosed |
| WO-2021061818-A1 | METHOD FOR INDUCING TUMOR REGRESSION | VEROSCIENCE LLC (US) | 2021-04-01 | — | — | WO | disclosed |
| US-20210085787-A1 | METHOD FOR INDUCING TUMOR REGRESSION | VEROSCIENCE LLC (US) | 2021-03-25 | — | — | US | disclosed |
| US-20040102383-A1 | Growth inhibition and eradication of solid tumors using neuroendocrine resetting therapy and photodynamic therapy | CINCOTTA ANTHONY H (US) | 2004-05-27 | — | — | US | disclosed |
| EP-0910365-B1 | GROWTH INHIBITION AND ERADICATION OF SOLID TUMORS USING A PROLACTIN MODULATOR AND A PHOTOSENSITIZER | GEN HOSPITAL CORP (US) | 2003-06-25 | — | — | EP | disclosed |
| US-20010049350-A1 | GROWTH INHIBITION AND ERADICATION OF SOLID TUMORS USING NEUROENDOCRINE RESETTING THERAPY AND PHOTODYNAMIC THERAPY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2001-12-06 | — | — | US | disclosed |
| EP-0910365-A4 | GROWTH INHIBITION AND ERADICATION OF SOLID TUMORS USING NEUROENDOCRINE RESETTING THERAPY AND PHOTODYNAMIC THERAPY | ERGO RESEARCH CORP (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0910365-A1 | GROWTH INHIBITION AND ERADICATION OF SOLID TUMORS USING NEUROENDOCRINE RESETTING THERAPY AND PHOTODYNAMIC THERAPY | Ergo Research Corporation (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997040829-A1 | GROWTH INHIBITION AND ERADICATION OF SOLID TUMORS USING NEUROENDOCRINE RESETTING THERAPY AND PHOTODYNAMIC THERAPY | ERGO RESEARCH CORPORATION (US) | 1997-11-06 | — | — | WO | disclosed |