Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3819373 | 0.98 | FDPS (0.49) | FDPSSMN1; SMN2ALDH1A1POLBNPC1 | |
| Hydrochloric Acid SCHEMBL19694075 | 0.98 | FDPS (0.49) | FDPSSMN1; SMN2ALDH1A1POLBNPC1 | |
| Hydrochloric Acid SCHEMBL19694078 | 0.98 | FDPS (0.49) | FDPSSMN1; SMN2ALDH1A1POLBNPC1 | |
| Hydrochloric Acid SCHEMBL8724693 | 0.98 | FDPS (0.49) | FDPSSMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL8494757 | 0.86 | KDM4E (0.52) | FDPSSMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL27974080 | 0.86 | KDM4E (0.52) | FDPSSMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL22346303 | 0.85 | FDPS (0.51) | FDPSSMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL22346302 | 0.85 | FDPS (0.51) | FDPSSMN1; SMN2ALDH1A1POLBNPC1 | |
| Hydrochloric Acid SCHEMBL22346290 | 0.83 | FDPS (0.50) | FDPSSMN1; SMN2ALDH1A1POLBNPC1 | |
| Hydrochloric Acid SCHEMBL22346291 | 0.83 | FDPS (0.50) | FDPSSMN1; SMN2ALDH1A1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031799-B1 | AROMATIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-9776962-B2 | Aromatic compounds with GPR40 agonistic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-10-03 | — | — | US | disclosed |
| EP-3031799-A1 | AROMATIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-06-15 | — | — | EP | disclosed |
| US-20160115128-A1 | AROMATIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115128-A1 | AROMATIC COMPOUND | GLP1R, GPR119, GPR39 | FDPS 3138/4885SMN1; SMN2 1516/4885ALDH1A1 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.