Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM4B | O94953 | 2/20 | 0.36 |
| ▸ | KDM5C | P41229 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533869 | 0.76 | METAP1 (0.36) | CHEK2KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL17701249 | 0.76 | CHEK2 (0.35) | CHEK2KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL745572 | 0.72 | — | — | |
| SCHEMBL17701250 | 0.72 | KDM4A (0.37) | CHEK2KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL17701231 | 0.69 | KDM4A (0.34) | KDM4AKDM4BKDM5CKDM5BMETAP1 | |
| SCHEMBL3778177 | 0.69 | CYP2A6 (0.48) | CHEK2CYP3A4CYP2C19TDO2 | |
| SCHEMBL743499 | 0.69 | CYP2D6 (0.41) | METAP2NPC1CYP2D6CYP2C19RAB9A | |
| SCHEMBL3245236 | 0.68 | CHEK2 (0.41) | CHEK2KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL15384267 | 0.68 | CHEK2 (0.48) | CHEK2KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL2724326 | 0.68 | CYP2A6 (0.53) | METAP2NPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160118598-A1 | ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | JNC CORPORATION (JP) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160118598-A1 | ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | HVCN1, VDAC1, SLC26A3 | CHEK2 4800/4885KDM4A 601/4885KDM4B 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.