Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748098 | 0.98 | ALDH1A1 (0.66) | ALDH1A1MAPTPKMGAANPC1 | |
| Ammonia Solution, Strong SCHEMBL26679975 | 0.96 | ALDH1A1 (0.63) | ALDH1A1MAPTPKMGAANPC1 | |
| Hydrochloric Acid SCHEMBL28519025 | 0.94 | ALDH1A1 (0.61) | ALDH1A1MAPTPKMGAANPC1 | |
| SCHEMBL27849608 | 0.92 | ALDH1A1 (0.65) | ALDH1A1MAPTPKMGAANPC1 | |
| Formamide SCHEMBL28482328 | 0.87 | ALDH1A1 (0.59) | ALDH1A1MAPTPKMGAANPC1 | |
| SCHEMBL28158484 | 0.82 | MAPT (0.52) | ALDH1A1MAPTPKMGAAMEN1 | |
| SCHEMBL3918916 | 0.79 | ALDH1A1 (0.63) | ALDH1A1MAPTPKMGAANPC1 | |
| SCHEMBL14127197 | 0.79 | ALDH1A1 (0.63) | ALDH1A1MAPTPKMGAANPC1 | |
| SCHEMBL316414 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTPKMGAANPC1 | |
| SCHEMBL11120842 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTPKMGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264097-A | Fluorescent probe for monitoring FAO level of living cells and macrophage polarization phenotype, and preparation method and application thereof | 贵州医科大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-105203512-B | A kind of carbazoles fluorescence probe and its preparation method and application | 山西大学 | 2018-02-06 | — | — | CN | disclosed |
| US-20110112149-A1 | EPOTHILONE ANALOGUES, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR USE AND THEIR PREPA RATIONS | TANG, LI (CN) | 2011-05-12 | — | — | US | disclosed |
| EP-2261221-A1 | EPOTHILONE ANALOGUES, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR USE AND THEIR PREPARATIONS | Tang, Li (CN) | 2010-12-15 | — | — | EP | disclosed |
| CN-1234026-C | Electric filter for electronic display | KYOWA YUKA KK (JP) | 2005-12-28 | — | — | CN | disclosed |
| CN-1435700-A | Electric filter for electronic display | KYOWA YUKA KK (JP) | 2003-08-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112149-A1 | EPOTHILONE ANALOGUES, THEIR PHARMACEUTICAL COMPOSITIONS, THEIR USE AND THEIR PREPA RATIONS | PPIA, PREP, THPO | ALDH1A1 2189/4885MAPT 3448/4885PKM 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.