Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748098 | 0.83 | ALDH1A1 (0.66) | MAPTALDH1A1PKMGAAALOX15 | |
| Ammonia Solution, Strong SCHEMBL26679975 | 0.82 | ALDH1A1 (0.63) | MAPTALDH1A1PKMGAAALOX15 | |
| Iodide SCHEMBL1770191 | 0.82 | ALDH1A1 (0.63) | MAPTALDH1A1PKMGAAALOX15 | |
| Hydrochloric Acid SCHEMBL28519025 | 0.80 | ALDH1A1 (0.61) | MAPTALDH1A1PKMGAAALOX15 | |
| SCHEMBL27849608 | 0.79 | ALDH1A1 (0.65) | MAPTALDH1A1PKMGAAALOX15 | |
| SCHEMBL14871610 | 0.78 | ALDH1A1 (0.54) | MAPTALDH1A1PKMACP1ALOX15 | |
| Formamide SCHEMBL28482328 | 0.78 | ALDH1A1 (0.59) | MAPTALDH1A1PKMACP1PPARG | |
| SCHEMBL27527885 | 0.76 | ALDH1A1 (0.53) | MAPTALDH1A1PKMACP1PPARG | |
| SCHEMBL27872889 | 0.76 | PKLR (0.39) | MAPTALDH1A1PKMACP1MEN1 | |
| Hydrochloric Acid SCHEMBL28217165 | 0.75 | PKLR (0.39) | MAPTALDH1A1PKMACP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967302-A | A kind of synthetic method of blood cell analysis dyestuff | 苏州康铭诚业医用科技有限公司 | 2017-07-21 | — | — | CN | disclosed |