Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | ADK | P55263 | 2/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898193 | 0.98 | ADORA3 (0.62) | ADORA3ADORA2AADORA1P2RY12 | |
| SCHEMBL28827066 | 0.90 | ADORA3 (0.52) | ADORA3ADORA2AADORA1P2RY12 | |
| SCHEMBL25605576 | 0.90 | ADORA3 (0.55) | ADORA3ADORA2AADORA1P2RY12 | |
| SCHEMBL26128147 | 0.87 | ADORA3 (0.48) | ADORA3ADORA2AADORA1P2RY12 | |
| SCHEMBL26128153 | 0.87 | ADORA3 (0.48) | ADORA3ADORA2AADORA1P2RY12 | |
| SCHEMBL26127012 | 0.84 | P2RY12 (0.49) | ADORA3ADORA2AP2RY12 | |
| SCHEMBL13208050 | 0.84 | ADORA3 (0.48) | ADORA3ADORA1P2RY12 | |
| SCHEMBL6908910 | 0.83 | P2RY12 (0.59) | ADORA3ADORA1P2RY12 | |
| SCHEMBL2986876 | 0.82 | ADORA3 (0.48) | ADORA3ADORA2AADORA1 | |
| SCHEMBL17706394 | 0.81 | PRMT6 (0.46) | ADORA3P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160355805-A1 | Double Stranded Oligonucleotide Compounds Comprising Positional Modifications | QUARK PHARMACEUTICALS, INC. | 2016-12-08 | — | — | US | disclosed |
| US-20160355805-A1 | Double Stranded Oligonucleotide Compounds Comprising Positional Modifications | QUARK PHARMACEUTICALS, INC. | 2016-12-08 | — | — | US | disclosed |
| EP-2649181-B1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOUNDS COMPRISING POSITIONAL MODIFICATIONS | QUARK PHARMACEUTICALS INC (US) | 2016-04-27 | — | — | EP | disclosed |