Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168321 | 0.80 | CYP2C19 (0.41) | MMP8CYP2D6CYP2C19PIK3CD | |
| SCHEMBL29059253 | 0.75 | CYP2D6 (0.32) | MMP8CYP2D6CYP2C19PIK3CD | |
| SCHEMBL29130087 | 0.75 | CYP2D6 (0.32) | MMP8CYP2D6CYP2C19PIK3CD | |
| SCHEMBL15562350 | 0.75 | CYP2D6 (0.32) | MMP8CYP2D6CYP2C19PIK3CD | |
| SCHEMBL28908979 | 0.73 | CYP2D6 (0.31) | CYP2D6CYP2C19 | |
| SCHEMBL29059387 | 0.73 | CYP2D6 (0.31) | CYP2D6CYP2C19 | |
| SCHEMBL28596003 | 0.72 | CYP2D6 (0.30) | CYP2D6CYP2C19 | |
| SCHEMBL29102325 | 0.72 | CYP2D6 (0.30) | CYP2D6CYP2C19 | |
| SCHEMBL29168294 | 0.69 | L3MBTL1 (0.30) | — | |
| SCHEMBL29050625 | 0.69 | ALDH1A1 (0.32) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776997-B2 | 3-aryl-substituted imidazo[1,2-A]pyridines and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-10-03 | — | — | US | disclosed |
| US-20160122341-A1 | 3-ARYL-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122341-A1 | 3-ARYL-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES AND THEIR USE | PNPO, PAH, TNNI3 | MMP8 3084/4885CYP2D6 133/4885CYP2C19 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.