SCHEMBL17712940

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23465973	0.89	NPC1 (0.62)	DRD2DRD3KCNH2CHRM1CHRM3
	SCHEMBL17713091	0.81	NPC1 (0.52)	DRD2DRD3KCNH2CHRM1CHRM3
	SCHEMBL17712859	0.80	DRD2 (0.54)	DRD2DRD3KCNH2CHRM1CHRM3
	SCHEMBL2966770	0.79	ALDH1A1 (0.53)	DRD2DRD3KCNH2CHRM1CHRM3
	SCHEMBL17712993	0.79	NPC1 (0.46)	DRD2DRD3NPC1RAB9AMEN1
	SCHEMBL4385569	0.78	DRD2 (0.71)	DRD2DRD3NPC1RAB9AMEN1
	SCHEMBL18758237	0.78	NPC1 (0.76)	DRD2DRD3KCNH2NPC1RAB9A
	SCHEMBL378553	0.78	DRD3 (0.54)	DRD2DRD3KCNH2NPC1RAB9A
	SCHEMBL17712887	0.77	DRD3 (0.51)	DRD2DRD3KCNH2NPC1RAB9A
	SCHEMBL17712729	0.77	HDAC3 (0.69)	DRD2NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.