Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | EYA2 | O00167 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799777 | 0.87 | TDP1 (0.52) | TSHROPRM1OPRD1OPRK1HDAC3 | |
| SCHEMBL2284795 | 0.85 | TDP1 (0.56) | TSHRHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17714019 | 0.84 | AKR1B1 (0.49) | TSHROPRM1OPRD1OPRK1HDAC3 | |
| SCHEMBL7564337 | 0.83 | TDP1 (0.58) | TSHRHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17714015 | 0.83 | AKR1B1 (0.47) | TSHROPRM1OPRD1OPRK1HDAC3 | |
| SCHEMBL12243695 | 0.81 | TDP1 (0.56) | TSHROPRM1OPRD1OPRK1HDAC3 | |
| SCHEMBL2807141 | 0.81 | TDP1 (0.56) | TSHRHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17714023 | 0.81 | OPRK1 (0.60) | OPRM1OPRD1OPRK1MEP1BDRD3 | |
| SCHEMBL212272 | 0.81 | AKR1B1 (0.52) | TSHRHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL20506819 | 0.81 | CA1 (0.51) | TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420910-B2 | Methods for low temperature fluorine-18 radiolabeling of biomolecules | KATHOLIEKE UNIVERSITET LEUVEN (BE) | 2022-08-23 | — | — | US | disclosed |
| EP-3212610-B1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | UNIV LEUVEN KATH (BE) | 2020-10-28 | — | — | EP | disclosed |
| US-20180273441-A1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-09-27 | — | — | US | disclosed |
| EP-3212610-A2 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | Katholieke Universiteit Leuven (BE) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016065435-A2 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2016-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180273441-A1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | H1-3, H1-0, H1-2 | TSHR 1114/4885OPRM1 3901/4885OPRD1 4266/4885 |
| US-11420910-B2 | Methods for low temperature fluorine-18 radiolabeling of biomolecules | H1-3, H1-0, H1-2 | TSHR 1095/4885OPRM1 3927/4885OPRD1 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.