Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 11/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.60 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674551 | 0.97 | OPRK1 (0.55) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL8423257 | 0.92 | OPRK1 (0.54) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL8421332 | 0.92 | OPRK1 (0.56) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL2799777 | 0.87 | TDP1 (0.52) | OPRK1OPRM1OPRD1DRD3MEP1B | |
| SCHEMBL2284795 | 0.85 | TDP1 (0.56) | DRD3MEP1B | |
| SCHEMBL7564337 | 0.83 | TDP1 (0.58) | DRD3 | |
| SCHEMBL12243695 | 0.81 | TDP1 (0.56) | OPRK1OPRM1OPRD1DRD3MEP1B | |
| SCHEMBL2807141 | 0.81 | TDP1 (0.56) | DRD3 | |
| SCHEMBL17714006 | 0.81 | TSHR (0.44) | OPRK1OPRM1OPRD1DRD3MEP1B | |
| SCHEMBL7759713 | 0.81 | MEP1B (0.51) | MEP1BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420910-B2 | Methods for low temperature fluorine-18 radiolabeling of biomolecules | KATHOLIEKE UNIVERSITET LEUVEN (BE) | 2022-08-23 | — | — | US | disclosed |
| EP-3212610-B1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | UNIV LEUVEN KATH (BE) | 2020-10-28 | — | — | EP | disclosed |
| US-20180273441-A1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-09-27 | — | — | US | disclosed |
| EP-3212610-A2 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | Katholieke Universiteit Leuven (BE) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016065435-A2 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2016-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180273441-A1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | H1-3, H1-0, H1-2 | OPRK1 4521/4885OPRM1 3901/4885OPRD1 4266/4885 |
| US-11420910-B2 | Methods for low temperature fluorine-18 radiolabeling of biomolecules | H1-3, H1-0, H1-2 | OPRK1 4521/4885OPRM1 3927/4885OPRD1 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.