SCHEMBL177151

SCHEMBL177151

O=[N+]([O-])c1cccc(I)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.70
LMNA P02545 2/20 0.70
ALDH1A1 P00352 6/20 0.57
ACHE P22303 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
ALOX15 P16050 1/20 0.57
HSP90AA1 P07900 1/20 0.55
GAA P10253 1/20 0.53
HTT P42858 1/20 0.53
KMT2A Q03164 1/20 0.53
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
TP53 P04637 1/20 0.52
TRPV1 Q8NER1 2/20 0.50
NFE2L2 Q16236 2/20 0.50
KEAP1 Q14145 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2903520 1.00 TSHR (0.70) TSHRLMNAALDH1A1ACHETDP1
Acetic Acid SCHEMBL31622747 0.89 ALDH1A1 (0.59) TSHRLMNAALDH1A1ACHETDP1
Acetic Acid SCHEMBL27720602 0.89 ALDH1A1 (0.59) TSHRLMNAALDH1A1ACHETDP1
Phenol SCHEMBL27479286 0.87 ALDH1A1 (0.65) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL27552634 0.87 TSHR (0.71) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL29291896 0.83 TSHR (1.00) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL36632 0.83 TSHR (1.00) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL29834109 0.80 TSHR (0.94) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL29143070 0.80 TSHR (0.94) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL11661349 0.80 TSHR (0.94) TSHRLMNAALDH1A1ACHETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250069948-A1 DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS LAM RESEARCH CORPORATION (US) 2025-02-27 US claimed
CN-116178092-B Preparation method of 1, 4-tetraphenyl-1, 3-butadiene and derivatives thereof 苏州大学 2024-11-22 CN claimed
CN-118874537-A Catalyst, preparation method thereof and method for preparing aromatic amine compound 厦门大学 2024-11-01 CN claimed
CN-118434908-A Metal deposition in recessed features using halogen-containing deposition inhibitors 朗姆研究公司 2024-08-02 CN claimed
CN-118320835-A Catalyst, preparation method thereof and method for preparing arylamine compound 厦门大学 2024-07-12 CN claimed
CN-118179542-A Carbon-based catalyst, and preparation method and application thereof 中国石油化工股份有限公司 2024-06-14 CN claimed
CN-117920223-A Application of magnetic iron-nickel spinel in preparation of aromatic amine compound by catalytic hydrogenation of aromatic nitro compound 兰州大学 2024-04-26 CN claimed
CN-114411169-B Photoelectrocatalysis hydrogen production and nitroarene in-situ hydrogenation integrated device and application 山西大学 2023-12-26 CN claimed
WO-2023114640-A1 DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS LAM RESEARCH CORPORATION (US) 2023-06-22 WO claimed
CN-116178092-A Preparation method of 1, 4-tetraphenyl-1, 3-butadiene and derivatives thereof 苏州大学 2023-05-30 CN claimed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO claimed
US-6420184-B1 PREPARING COMPOSITION FOR USE IN THERMOMETER; OBTAIN SAMPLE, CONVERT TO LIQUID, EMULSIFY, COOL EMULSION AND SOLIDIFY 3M INNOVATIVE PROPERTIES COMPANY 2002-07-16 US claimed
US-20020015826-A1 Zwitterionic iodonium compounds and methods of application CLEMSON UNIVERSITY 2002-02-07 US claimed
US-5816707-A Reversible chemical thermometer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-06 US claimed
EP-0684463-A1 Temperature indicating device and composition for use therein PyMaH Corporation (US) 1995-11-29 EP claimed
US-5094545-A Solid solution with nucleating agent and indicator dye PYMA CORPORATION (US) 1992-03-10 US claimed
EP-0070198-B1 RADIATION-SENSITIVE COMPOSITION AND PATTERN-FORMATION METHOD USING THE SAME Hitachi, Ltd. (JP) 1985-06-19 EP claimed
EP-0070198-A1 Radiation-sensitive composition and pattern-formation method using the same Hitachi, Ltd. (JP) 1983-01-19 EP claimed
US-4232552-A THERMOCHROMISM, DISPOSABLE THERMOMETERS AKZONA INCORPORATED (US) 1980-11-11 US claimed
US-4150572-A HEAT SENSITIVE MIXTURE OF LOW MOLECULAR WEIGHT ORGANIC COMPOUND AND POLYMER JOHNSON & JOHNSON (US) 1979-04-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020015826-A1 Zwitterionic iodonium compounds and methods of application DGKI, DSTN, PCNA TSHR 2242/4885LMNA 3231/4885ALDH1A1 3578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.