SCHEMBL2903520

SCHEMBL2903520

O=[N+]([O-])c1cccc(I)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.70
LMNA P02545 2/20 0.70
ALDH1A1 P00352 6/20 0.57
ACHE P22303 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
ALOX15 P16050 1/20 0.57
HSP90AA1 P07900 1/20 0.55
GAA P10253 1/20 0.53
HTT P42858 1/20 0.53
KMT2A Q03164 1/20 0.53
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
TP53 P04637 1/20 0.52
TRPV1 Q8NER1 2/20 0.50
NFE2L2 Q16236 2/20 0.50
KEAP1 Q14145 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL177151 1.00 TSHR (0.70) TSHRLMNAALDH1A1ACHETDP1
Acetic Acid SCHEMBL31622747 0.89 ALDH1A1 (0.59) TSHRLMNAALDH1A1ACHETDP1
Acetic Acid SCHEMBL27720602 0.89 ALDH1A1 (0.59) TSHRLMNAALDH1A1ACHETDP1
Phenol SCHEMBL27479286 0.87 ALDH1A1 (0.65) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL27552634 0.87 TSHR (0.71) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL29291896 0.83 TSHR (1.00) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL36632 0.83 TSHR (1.00) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL29834109 0.80 TSHR (0.94) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL29143070 0.80 TSHR (0.94) TSHRLMNAALDH1A1ACHETDP1
Dinitrophenylene SCHEMBL11661349 0.80 TSHR (0.94) TSHRLMNAALDH1A1ACHETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4448831-A1 DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS Lam Research Corporation (US) 2024-10-23 EP claimed
WO-2023114640-A1 DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS LAM RESEARCH CORPORATION (US) 2023-06-22 WO claimed
US-20250188046-A1 ULTRAFAST FLOW SYNTHESIS OF FUNCTIONALIZED SULFONYL FLUORIDES AND SUBSEQUENT SUFEX CONNECTIONS VIA LITHIATED CHEMISTRY POSTECH Research and Business Development Foundation (KR) 2025-06-12 US disclosed
EP-4448831-A1 DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS Lam Research Corporation (US) 2024-10-23 EP disclosed
WO-2024013308-A2 METHOD OF REDUCING NITRO COMPOUNDS THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2024-01-18 WO disclosed
WO-2023114640-A1 DEPOSITION OF METALS IN RECESSED FEATURES WITH THE USE OF HALOGEN-CONTAINING DEPOSITION INHIBITORS LAM RESEARCH CORPORATION (US) 2023-06-22 WO disclosed
WO-2023093845-A1 CHIMERIC COMPOUND FOR TARGETED DEGRADATION OF ANDROGEN RECEPTOR PROTEIN, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF 江苏恒瑞医药股份有限公司 2023-06-01 WO disclosed
EP-4153576-A1 NOTCH INHIBITORS AND USES THEREOF StemSynergy Therapeutics, Inc. (US) 2023-03-29 EP disclosed
WO-2022261352-A1 PERFLUOROALKANE SUBSTITUTED PYRAZOLO[3,4-D]PYRIMIDIN AND PYRROLO[2,3-D]PYRIMIDIN COMPOUNDS AND USES THEREOF ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2022-12-15 WO disclosed
EP-1253470-B1 Radiation-sensitive resin composition JSR CORP (JP) 2010-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188046-A1 ULTRAFAST FLOW SYNTHESIS OF FUNCTIONALIZED SULFONYL FLUORIDES AND SUBSEQUENT SUFEX CONNECTIONS VIA LITHIATED CHEMISTRY FGFR4, STS, FGFR1 TSHR 1782/4885LMNA 3753/4885ALDH1A1 1626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.