Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923095 | 0.76 | P2RY12 (0.53) | MAPTKDM4EALDH1A1CASP3 | |
| SCHEMBL12161552 | 0.74 | P2RY12 (0.44) | MAPTKDM4ECA12CA1CA9 | |
| SCHEMBL5148489 | 0.67 | HDAC1 (0.45) | MAPTKDM4EGAAGFERPEPD | |
| SCHEMBL9919110 | 0.66 | ADORA3 (0.42) | KDM4EGAAL3MBTL1TP53MAPK1 | |
| SCHEMBL6982187 | 0.63 | GAA (0.59) | MAPTKDM4EGAATP53CA12 | |
| SCHEMBL31078349 | 0.63 | KDM4E (0.52) | KDM4EL3MBTL1MAPK1HSD17B10 | |
| SCHEMBL11669959 | 0.63 | KDM4E (0.52) | KDM4EL3MBTL1MAPK1HSD17B10 | |
| SCHEMBL4956958 | 0.63 | LMNA (0.72) | MAPTGAATP53MAPK1ALDH1A1 | |
| Phenylurea SCHEMBL28313006 | 0.62 | GAA (0.79) | MAPTGAAGFERL3MBTL1PEPD | |
| SCHEMBL28791705 | 0.62 | ALDH1A1 (0.51) | MAPTKDM4EGAAGFERPEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314593-B1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARM INC (US) | 2016-05-04 | — | — | EP | disclosed |