Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PARG | Q86W56 | 5/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29558921 | 0.87 | PIK3CG (0.47) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL54882 | 0.87 | PIK3CG (0.47) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL3761642 | 0.80 | ATM (0.51) | PIK3CGHTTNPC1RAB9AHCRTR1 | |
| SCHEMBL27651563 | 0.72 | MAPT (0.54) | PIK3CGHTTTAS2R14MEN1KMT2A | |
| SCHEMBL20855010 | 0.71 | PIK3CG (0.47) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL17832062 | 0.71 | PIK3CG (0.72) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL26090948 | 0.70 | PARG (0.64) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL14392546 | 0.70 | LMNA (0.36) | LMNAATML3MBTL1 | |
| SCHEMBL17825124 | 0.69 | PARG (0.61) | PIK3CGPARGPKMHTTMITF | |
| SCHEMBL5865904 | 0.67 | PARG (0.47) | PIK3CGPARGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152258-B1 | DERIVATIVES OF FLUORENE, ANTHRACENE, XANTHENE, DIBENZOSUBERONE AND ACRIDINE AND USES THEREOF | AVALON PHARMACEUTICALS (US) | 2016-05-04 | — | — | EP | disclosed |