SCHEMBL17716634

SCHEMBL17716634

N#CCCC1(CCC#N)C(=O)N(Cc2ccccc2)C(=O)N(c2ccccc2)C1=O

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.52
ELANE P08246 10/20 0.48
ALDH1A1 P00352 2/20 0.42
CYP2C19 P33261 1/20 0.42
CTSG P08311 2/20 0.41
F2 P00734 1/20 0.41
PLG P00747 1/20 0.41
CMA1 P23946 1/20 0.41
CTRC Q99895 1/20 0.41
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
MGLL Q99685 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PRTN3 P24158 1/20 0.36
ENPP2 Q13822 1/20 0.36
MAPK1 P28482 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17716635 0.86 ELANE (0.53) ELANEALDH1A1CYP2C19MGLLMAPK1
SCHEMBL17716645 0.74 ALDH1A1 (0.46) ELANEALDH1A1CYP2C19MGLLMEN1
SCHEMBL16865386 0.71 ELANE (0.51) NPSR1ELANEALDH1A1CYP2C19CTSG
SCHEMBL16865412 0.70 SCN9A (0.53) NPSR1ELANECYP2C19CTSGF2
SCHEMBL16865411 0.70 ELANE (0.50) NPSR1ELANEALDH1A1CYP2C19CTSG
SCHEMBL17716265 0.70 ELANE (0.72) NPSR1ELANEALDH1A1CYP2C19CTSG
SCHEMBL16865413 0.70 ELANE (0.50) NPSR1ELANEALDH1A1CTSGF2
SCHEMBL16865419 0.70 NPSR1 (0.54) NPSR1ELANECYP2C19CTSGF2
SCHEMBL17716262 0.69 NPSR1 (0.74) NPSR1ELANECTSGF2PLG
SCHEMBL4428745 0.69 ELANE (0.74) NPSR1ELANEALDH1A1CYP2C19CTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9718933-B2 Optical film, and polarizing plate and liquid crystal display device employing same FUJIFILM CORPORATION (JP) 2017-08-01 US disclosed
US-20160122486-A1 OPTICAL FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE EMPLOYING SAME FUJIFILM CORPORATION (JP) 2016-05-05 US disclosed