Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15293381 | 0.98 | TSHR (0.57) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10331158 | 0.94 | TSHR (0.57) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL9962957 | 0.93 | TSHR (0.55) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10331155 | 0.93 | MEN1 (0.60) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL139326 | 0.93 | TSHR (0.55) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10030114 | 0.93 | TSHR (0.55) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL17716670 | 0.92 | TSHR (0.54) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10331153 | 0.92 | TSHR (0.48) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL2406752 | 0.92 | TSHR (0.50) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL16706197 | 0.91 | TSHR (0.53) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312977-A1 | SILICONE CHAIN-CONTAINING POLYMER AND COATING COMPOSITION CONTAINING SAID POLYMER | DIC CORPORATION (JP) | 2023-10-05 | — | — | US | disclosed |
| US-20230242808-A1 | PHOTOCHROMIC COMPOUND AND CURABLE COMPOSITION CONTAINING THE PHOTOCHROMIC COMPOUND | TOKUYAMA CORPORATION (JP) | 2023-08-03 | — | — | US | disclosed |
| US-20180120702-A1 | TETRACARBOXYLIC ACID DIESTER COMPOUND, POLYMER OF POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING SAME, NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, AND METHOD FOR FORMING CURED FILM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-05-03 | — | — | US | disclosed |
| US-20180044518-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2018-02-15 | — | — | US | disclosed |
| US-9815979-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9617423-B2 | Macroinitiator containing hydrophobic segment | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| US-20170051145-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2017-02-23 | — | — | US | disclosed |
| US-9522980-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160194497-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | JOHNSON & JOHNSON VISION CARE (US) | 2016-07-07 | — | — | US | disclosed |
| US-9321890-B2 | Macroinitiator containing hydrophobic segment | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20120071570-A1 | NOVEL ACYL ACIDIC AMINO ACID ESTER | AJINOMOTO CO., INC. (JP) | 2012-03-22 | — | — | US | disclosed |
| US-20120022180-A1 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED | 2012-01-26 | — | — | US | disclosed |
| US-8101701-B2 | having a hydrophilic group and a silicon-containing alkyl group within molecule; lenses with high oxygen permeability independent from the water content may be obtained, wherein the fumaric acid derivatives is superior in compatibility with the hydrophilic monomer used in combination | MENICON NECT CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20110275734-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2011-11-10 | — | — | US | disclosed |
| US-8043369-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2011-10-25 | — | — | US | disclosed |
| US-20110147681-A1 | Photochromic Polymer and Composition Comprising Photochromic Polymer | ADVANCED POLYMERIK PTY LTD (AU) | 2011-06-23 | — | — | US | disclosed |
| US-20100317809-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100305231-A1 | POLYMER NETWORKS, PROCESS FOR PRODUCING SAME, AND PRODUCTS MADE THEREFROM | THE UNIVERSITY OF AKRON (US) | 2010-12-02 | — | — | US | disclosed |
| US-20090263663-A1 | Acrylic resin composition and molded product using the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20080132666-A1 | Fumaric Acid Derivatives and Ophthalmic Lenses Using the Same | MENICON NECT CO., LTD. (JP) | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132666-A1 | Fumaric Acid Derivatives and Ophthalmic Lenses Using the Same | FAH, FH, AQP4 | TSHR 4064/4885MEN1 423/4885KMT2A 2397/4885 |
| US-20180120702-A1 | TETRACARBOXYLIC ACID DIESTER COMPOUND, POLYMER OF POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING SAME, NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, AND METHOD FOR FORMING CURED FILM | TET1, KDM1A, KDM2B | TSHR 3618/4885MEN1 1695/4885KMT2A 102/4885 |
| US-20120071570-A1 | NOVEL ACYL ACIDIC AMINO ACID ESTER | FFAR2, FFAR1, FFAR3 | TSHR 3923/4885MEN1 647/4885KMT2A 1103/4885 |
| US-20110147681-A1 | Photochromic Polymer and Composition Comprising Photochromic Polymer | SMCHD1, PCNA, PARG | TSHR 4564/4885MEN1 4274/4885KMT2A 1475/4885 |
| US-20230242808-A1 | PHOTOCHROMIC COMPOUND AND CURABLE COMPOSITION CONTAINING THE PHOTOCHROMIC COMPOUND | RB1, CRY2, CDK16 | TSHR 3842/4885MEN1 2676/4885KMT2A 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.