Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 6/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176935 | 0.89 | HCRTR2 (0.43) | HCRTR2MAOBNR1H3ATMTSHR | |
| SCHEMBL177398 | 0.88 | MAOB (0.47) | HCRTR2MAOBATMABCB1ABCC1 | |
| SCHEMBL11897109 | 0.85 | MAOB (0.45) | HCRTR2MAOBATMABCB1ABCC1 | |
| SCHEMBL177448 | 0.84 | SRD5A2 (0.46) | MAOB | |
| SCHEMBL11897265 | 0.84 | MAOB (0.44) | HCRTR2MAOBNR1H3ATMABCB1 | |
| SCHEMBL177178 | 0.83 | ATM (0.40) | HCRTR2MAOBNR1H3ATMTSHR | |
| SCHEMBL11898451 | 0.82 | HCRTR2 (0.40) | HCRTR2MAOBNR1H3ATMTSHR | |
| SCHEMBL177305 | 0.82 | PPARG (0.48) | ATM | |
| SCHEMBL177347 | 0.81 | ATM (0.38) | HCRTR2MAOBNR1H3ATM | |
| SCHEMBL176959 | 0.81 | NR1H3 (0.37) | HCRTR2MAOBNR1H3ATMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120225909-A1 | INDAZOLE ANALOG | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-09-06 | — | — | US | disclosed |
| EP-2484668-A1 | INDAZOLE ANALOGUE | Asahi Kasei Pharma Corporation (JP) | 2012-08-08 | — | — | EP | disclosed |
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225909-A1 | INDAZOLE ANALOG | ADRB3, ADRB1, ADRB2 | HCRTR2 237/4885MAOB 605/4885NR1H3 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.