SCHEMBL17717907

SCHEMBL17717907

O=C1NC(=O)N(CCOCCN2C(=O)NC(=O)C(Cc3ccccc3)C2=O)C(=O)C1Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.48
ALDH1A1 P00352 5/20 0.42
HTT P42858 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GLA P06280 1/20 0.42
HRH3 Q9Y5N1 1/20 0.41
POLB P06746 2/20 0.40
GAA P10253 1/20 0.40
CES2 O00748 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
KDM4C Q9H3R0 1/20 0.39
HDAC8 Q9BY41 2/20 0.39
PLA2G10 O15496 1/20 0.39
PLA2G5 P39877 1/20 0.39
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17717901 0.85 EP300 (0.50) EP300ALDH1A1HTTMAPTKDM4E
SCHEMBL18254504 0.84 EP300 (0.49) EP300ALDH1A1HTTMAPTKDM4E
SCHEMBL15978137 0.83 EP300 (0.48) EP300ALDH1A1HTTMAPTKDM4E
SCHEMBL7844009 0.82 EP300 (0.66) EP300ALDH1A1POLBGAAMEN1
SCHEMBL15978110 0.82 MMP1 (0.52) EP300ALDH1A1HTTMAPTKDM4E
SCHEMBL5831498 0.81 EP300 (0.43) EP300ALDH1A1HTTMAPTKDM4E
SCHEMBL18257385 0.81 SMN1; SMN2 (0.47) ALDH1A1HTTMAPTMEN1KMT2A
SCHEMBL17717902 0.78 EP300 (0.56) EP300ALDH1A1HTTMAPTKDM4E
SCHEMBL17864856 0.78 SMN1; SMN2 (0.41) EP300ALDH1A1HTTMAPTKDM4E
SCHEMBL2673247 0.77 KDM4C (0.50) EP300ALDH1A1MAPTKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160122516-A1 OPTICAL FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE EMPLOYING SAME FUJIFILM CORPORATION (JP) 2016-05-05 US disclosed
US-20160122516-A1 OPTICAL FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE EMPLOYING SAME FUJIFILM CORPORATION (JP) 2016-05-05 US disclosed