SCHEMBL2673247

SCHEMBL2673247

CN1C(=O)NC(=O)C(Cc2ccccc2)C1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
CES2 O00748 3/20 0.48
PLA2G10 O15496 1/20 0.47
PLA2G5 P39877 1/20 0.47
EP300 Q09472 1/20 0.46
GFER P55789 1/20 0.44
MMP1 P03956 1/20 0.43
MMP3 P08254 1/20 0.43
MMP9 P14780 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.42
POLB P06746 2/20 0.42
KDM4A O75164 1/20 0.42
USP2 O75604 1/20 0.42
ALOX15 P16050 1/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPT P10636 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2672281 0.84 SLC18A2 (0.41) KDM4CMEN1KMT2AL3MBTL1POLB
SCHEMBL2672873 0.82 HSD17B2 (0.43) MEN1KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL17717901 0.80 EP300 (0.50) MEN1KMT2ACES2PLA2G10PLA2G5
SCHEMBL15978110 0.79 MMP1 (0.52) KDM4CMEN1KMT2ACES2PLA2G10
SCHEMBL4435666 0.79 KMT2A (0.72) KDM4CMEN1KMT2ACES2PLA2G10
SCHEMBL472396 0.79 ALDH1A1 (0.56) KDM4CMEN1KMT2ACES2EP300
SCHEMBL7844009 0.79 EP300 (0.66) MEN1KMT2AEP300POLBALDH1A1
SCHEMBL2672633 0.78 CES2 (0.48) KDM4CMEN1KMT2ACES2L3MBTL1
SCHEMBL18254504 0.78 EP300 (0.49) MEN1KMT2ACES2PLA2G10PLA2G5
SCHEMBL17070925 0.78 CES2 (0.49) KDM4CMEN1KMT2ACES2PLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10871597-B2 Polarizing plate, image display device, and polarizing plate protective film FUJIFILM CORPORATION (JP) 2020-12-22 US disclosed
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-10338290-B2 Cellulose ester film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-20170322358-A1 POLARIZING PLATE, FRONT PANEL OF DISPLAY DEVICE, DISPLAY APPARATUS, SUBSTRATE OF TOUCH PANEL, RESISTIVE FILM-TYPE TOUCH PANEL, AND CAPACITANCE-TYPE TOUCH PANEL FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-20170322358-A1 POLARIZING PLATE, FRONT PANEL OF DISPLAY DEVICE, DISPLAY APPARATUS, SUBSTRATE OF TOUCH PANEL, RESISTIVE FILM-TYPE TOUCH PANEL, AND CAPACITANCE-TYPE TOUCH PANEL FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-9551813-B2 Optical film, polarizing plate using same, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-01-24 US disclosed
US-20160370522-A1 CELLULOSE ESTER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20140242302-A1 LAMINATE, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed
US-20140242300-A1 POLARIZER, POLARIZING PLATE USING THE SAME, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed
US-20140242300-A1 POLARIZER, POLARIZING PLATE USING THE SAME, LIQUID CRYSTAL DISPLAY DEVICE, AND METHOD OF MANUFACTURING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2014-08-28 US disclosed
US-8173664-B2 Modified pyrimidine glucocorticoid receptor modulators CORCEPT THERAPEUTICS, INC. (US) 2012-05-08 US disclosed
EP-1778236-B1 MODIFIED PYRIMIDINE GLUCOCORTICOID RECEPTOR MODULATORS CORCEPT THERAPEUTICS INC (US) 2010-07-14 EP disclosed
US-20090275600-A1 MODIFIED PYRIMIDINE GLUCOCORTICOID RECEPTOR MODULATORS CORCEPT THERAPEUTICS, INC. (US) 2009-11-05 US disclosed
US-7576076-B2 Modified pyrimidine glucocorticoid receptor modulators CORCEPT THERAPEUTICS, INC. (US) 2009-08-18 US disclosed
EP-1778236-A1 MODIFIED PYRIMIDINE GLUCOCORTICOID RECEPTOR MODULATORS Corcept Therapeutics, Inc. (US) 2007-05-02 EP disclosed
WO-2006014394-A1 MODIFIED PYRIMIDINE GLUCOCORTICOID RECEPTOR MODULATORS CORCEPT THERAPEUTICS, INC. (US) 2006-02-09 WO disclosed
US-20060025405-A1 Modified pyrimidine glucocorticoid receptor modulators CORCEPT THERAPEUTICS, INC. (US) 2006-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060025405-A1 Modified pyrimidine glucocorticoid receptor modulators NR3C1, NR3C2, TYMS KDM4C 2673/4885MEN1 4371/4885KMT2A 2535/4885
US-20090275600-A1 MODIFIED PYRIMIDINE GLUCOCORTICOID RECEPTOR MODULATORS NR3C1, NR3C2, TYMS KDM4C 2673/4885MEN1 4371/4885KMT2A 2535/4885
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device NBAS, SSB, GNA15 KDM4C 4383/4885MEN1 2124/4885KMT2A 3675/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 KDM4C 4413/4885MEN1 2234/4885KMT2A 3866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.