SCHEMBL17864856

SCHEMBL17864856

O=C(NCc1cccc(CNC(=O)OCCN2C(=O)NC(=O)C(Cc3ccccc3)C2=O)c1)OCCN1C(=O)NC(=O)C(Cc2ccccc2)C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.41
PADI3 Q9ULW8 1/20 0.39
PADI4 Q9UM07 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA2B P29275 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39
ALDH1A1 P00352 5/20 0.36
POLB P06746 2/20 0.36
KDM4E B2RXH2 2/20 0.36
EP300 Q09472 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HTT P42858 2/20 0.36
MAPT P10636 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19587709 0.90 SMN1; SMN2 (0.41) SMN1; SMN2PADI3PADI4ADORA2AADORA2B
SCHEMBL18257385 0.84 SMN1; SMN2 (0.47) SMN1; SMN2MEN1KMT2AALDH1A1HSD17B10
SCHEMBL18257375 0.79 HDAC3 (0.39) MEN1KMT2AIDO1TDO2ALDH1A1
SCHEMBL17717907 0.78 EP300 (0.48) SMN1; SMN2MEN1KMT2AALDH1A1POLB
SCHEMBL18254504 0.77 EP300 (0.49) MEN1KMT2ACYP3A4ALDH1A1POLB
SCHEMBL17717902 0.74 EP300 (0.56) MEN1KMT2ACYP3A4CYP2C9ALDH1A1
SCHEMBL20878123 0.74 IDO1 (0.34) SMN1; SMN2MEN1KMT2AIDO1TDO2
SCHEMBL17886028 0.73 TDP1 (0.38) SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9
SCHEMBL17717901 0.73 EP300 (0.50) MEN1KMT2AALDH1A1POLBKDM4E
SCHEMBL17346754 0.72 LMNA (0.56) SMN1; SMN2PADI3PADI4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-10338277-B2 Polarizing plate protective film, polarizing plate, and display FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-10253201-B2 Composition for polarizing plate, polarizing plate protective film, cellulose acylate film, polarizer, polarizing plate, and display FUJIFILM CORPORATION (JP) 2019-04-09 US disclosed
US-10031264-B2 Polarizing plate and display device FUJIFILM CORPORATION (JP) 2018-07-24 US disclosed
US-9817156-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-11-14 US disclosed
US-20170322358-A1 POLARIZING PLATE, FRONT PANEL OF DISPLAY DEVICE, DISPLAY APPARATUS, SUBSTRATE OF TOUCH PANEL, RESISTIVE FILM-TYPE TOUCH PANEL, AND CAPACITANCE-TYPE TOUCH PANEL FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9678249-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed
US-20160341860-A1 POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE INCLUDING SAME, AND METHOD FOR PRODUCING POLARIZING PLATE FUJIFILM CORPORATION (JP) 2016-11-24 US disclosed
US-20160291210-A1 POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291211-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291213-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-20160185993-A1 COMPOSITION FOR POLARIZING PLATE, POLARIZING PLATE PROTECTIVE FILM, CELLULOSE ACYLATE FILM, POLARIZER, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-06-30 US disclosed
US-20160178809-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device NBAS, SSB, GNA15 SMN1; SMN2 2279/4885PADI3 1739/4885PADI4 1662/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 SMN1; SMN2 2393/4885PADI3 1224/4885PADI4 1691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.