SCHEMBL25821865

SCHEMBL25821865

CC[C@H]1O[C@@](C#N)(c2cc(I)c3c(N)ncnn23)[C@H](OCc2ccccc2)[C@@H]1C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TNK2 Q07912 2/20 0.32
▸ PIK3CD O00329 6/20 0.31
▸ NTRK1 P04629 1/20 0.31
▸ NTRK2 Q16620 1/20 0.31
▸ EGLN2 Q96KS0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17719232 0.85 TMPRSS2 (0.35) TNK2
SCHEMBL18623842 0.85 TMPRSS2 (0.35) TNK2
SCHEMBL10120684 0.85 TMPRSS2 (0.35) TNK2
SCHEMBL17719370 0.85 TMPRSS2 (0.35) TNK2
SCHEMBL23960050 0.84 PDE2A (0.34) TNK2EGLN2
SCHEMBL17719377 0.77 RIPK1 (0.31) TNK2
SCHEMBL10120843 0.77 RIPK1 (0.31) TNK2
SCHEMBL17719234 0.77 — —
SCHEMBL17719358 0.77 — —
SCHEMBL23960007 0.75 PDE2A (0.34) TNK2EGLN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES MIRACURE BIOTECHNOLOGY LTD (CN) 2023-10-26 — — US disclosed
US-20230219993-A1 ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG VIGONVITA LIFE SCIENCES CO., LTD. (CN) 2023-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219993-A1 ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG PNP, TYMP, PIGS TNK2 1979/4885PIK3CD 774/4885NTRK1 4110/4885
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES PNP, MTAP, TYMP TNK2 2454/4885PIK3CD 1909/4885NTRK1 4813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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