SCHEMBL177241

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL176976	0.77	EPHX1 (0.44)	THRATHRBESR1ADRA2AADORA3
	SCHEMBL177243	0.77	SPHK1 (0.48)	S1PR1S1PR3S1PR2S1PR4THRA
	SCHEMBL31103625	0.76	GNAI3 (0.50)	S1PR1S1PR3S1PR2S1PR4S1PR5
	SCHEMBL565825	0.73	S1PR1 (0.49)	S1PR1S1PR3S1PR2S1PR4LPAR2
	SCHEMBL177606	0.73	SPHK1 (0.45)	THRATHRBESR1ADRA2AADORA3
	SCHEMBL177607	0.73	SPHK1 (0.46)	THRATHRBESR1ADRA2AADORA3
	SCHEMBL177242	0.73	SPHK1 (0.46)	S1PR1S1PR3S1PR4S1PR5THRA
	SCHEMBL13100484	0.73	HDAC6 (0.55)	S1PR1S1PR3S1PR2S1PR4LPAR2
	SCHEMBL13093992	0.71	MEN1 (0.44)	S1PR1S1PR3S1PR2S1PR4LPAR2
	SCHEMBL19217017	0.71	S1PR1 (0.73)	S1PR1S1PR3S1PR2S1PR4LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.