SCHEMBL41269

SCHEMBL41269

O=C(O)CNCOC[C@@H]1O[C@H](n2ccc(=O)[nH]c2=S)C(O)C1O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY14 Q15391 8/20 0.55
P2RY2 P41231 9/20 0.54
P2RY6 Q15077 8/20 0.54
P2RY4 P51582 4/20 0.54
SLC28A1 O00337 1/20 0.47
SLC28A2 O43868 1/20 0.47
SLC29A1 Q99808 1/20 0.47
SLC28A3 Q9HAS3 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366853 1.00 P2RY14 (0.55) P2RY14P2RY2P2RY6P2RY4SLC28A1
SCHEMBL552611 0.90 SLC28A1 (0.60) P2RY14P2RY2P2RY6P2RY4SLC28A1
SCHEMBL28714767 0.86 P2RY14 (0.59) P2RY14P2RY2P2RY6P2RY4SLC28A1
SCHEMBL17728069 0.85 P2RY14 (0.61) P2RY14P2RY2P2RY6P2RY4SLC28A1
SCHEMBL6754596 0.84 P2RY14 (0.61) P2RY14P2RY2P2RY6P2RY4SLC28A1
SCHEMBL17065224 0.83 P2RY14 (0.54) P2RY14P2RY2P2RY6P2RY4SLC28A1
SCHEMBL7611038 0.82 P2RY14 (0.61) P2RY14P2RY2P2RY6P2RY4SLC28A1
SCHEMBL5964450 0.82 P2RY14 (0.61) P2RY14P2RY2P2RY6P2RY4SLC28A1
SCHEMBL19462556 0.80 P2RY2 (0.47) P2RY14P2RY2P2RY6P2RY4SLC28A1
SCHEMBL6028058 0.80 P2RY14 (0.69) P2RY14P2RY2P2RY6P2RY4SLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 640 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748382-A2 PRODUCTS AND COMPOSITIONS Silence Therapeutics GmbH (DE) 2026-05-27 EP disclosed
EP-4748381-A2 PRODUCTS AND COMPOSITIONS Silence Therapeutics GmbH (DE) 2026-05-27 EP disclosed
US-20260109983-A1 HIPPO AND DYSTROPHIN COMPLEX SIGNALING IN CARDIOMYOCYTE RENEWAL BAYLOR COLLEGE OF MEDICINE (US) 2026-04-23 US disclosed
EP-3826720-B1 NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF TMPRSS6 AND IRON CHELATORS SILENCE THERAPEUTICS GMBH (DE) 2026-04-22 EP disclosed
EP-4717773-A2 NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF A TARGET GENE COMPRISING PHOSPHORODITHIOATE LINKAGES Silence Therapeutics GmbH (DE) 2026-04-01 EP disclosed
US-20260078372-A1 NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF LPA IN A CELL SILENCE THERAPEUTICS GMBH (DE) 2026-03-19 US disclosed
EP-3710585-B1 NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF A TARGET GENE COMPRISING PHOSPHORODITHIOATE LINKAGES SILENCE THERAPEUTICS GMBH (DE) 2026-02-25 EP disclosed
EP-4674963-A2 HIPPO AND DYSTROPHIN COMPLEX SIGNALING IN CARDIOMYOCYTE RENEWAL Baylor College of Medicine (US) 2026-01-07 EP disclosed
US-12497466-B2 Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities ATYR PHARMA, INC. (US) 2025-12-16 US disclosed
US-12480120-B2 Hippo and dystrophin complex signaling in cardiomyocyte renewal BAYLOR COLLEGE OF MEDICINE (US) 2025-11-25 US disclosed
US-20020177568-A1 Enzymatic nucleic acid treatment of diseases or conditions related to levels of NF-kappa B RIBOZYME PHARMACEUTICALS, INC. 2002-11-28 US disclosed
WO-2002094185-A2 CONJUGATES AND COMPOSITIONS FOR CELLULAR DELIVERY SIRNA THERAPEUTICS, INC. (US) 2002-11-28 WO disclosed
EP-1257639-A2 NUCLEOZYMES WITH ENDONUCLEASE ACTIVITY RIBOZYME PHARMACEUTICALS, INC. (US) 2002-11-20 EP disclosed
WO-2001059103-A9 METHOD AND REAGENT FOR THE MODULATION AND DIAGNOSIS OF CD20 AND NOGO GENE EXPRESSION RIBOZYME PHARM INC (US) 2002-10-24 WO disclosed
US-20020142980-A1 Nucleic acid molecules with novel chemical compositions capable of modulating gene expression RIBOZYME PHARMACEUTICALS INC. 2002-10-03 US disclosed
US-20020102568-A1 Nucleic acid sensor molecules RIBOZYME PHARMACEUTICALS, INC. 2002-08-01 US disclosed
WO-2001066721-A2 NUCLEIC ACID SENSOR MOLECULES RIBOZYME PHARMACEUTICALS, INC. (US) 2001-09-13 WO disclosed
WO-2001059102-A2 NUCLEOZYMES WITH ENDONUCLEASE ACTIVITY RIBOZYME PHARMACEUTICALS, INC. (US) 2001-08-16 WO disclosed
WO-2001059103-A2 METHOD AND REAGENT FOR THE MODULATION AND DIAGNOSIS OF CD20 AND NOGO GENE EXPRESSION RIBOZYME PHARMACEUTICALS, INC. (US) 2001-08-16 WO disclosed
WO-2001057206-A2 METHOD AND REAGENT FOR THE INHIBITION OF CHECKPOINT KINASE-1 (CHK 1) ENZYME RIBOZYME PHARMACEUTICALS, INC. (US) 2001-08-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109983-A1 HIPPO AND DYSTROPHIN COMPLEX SIGNALING IN CARDIOMYOCYTE RENEWAL ACTN1, TNNC1, MYLK2 P2RY14 4199/4885P2RY2 4052/4885P2RY6 4279/4885
US-20020102568-A1 Nucleic acid sensor molecules ZFR, GDA, ADAR P2RY14 1667/4885P2RY2 3137/4885P2RY6 2355/4885
US-20260078372-A1 NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF LPA IN A CELL LPAR2, LPCAT1, LPAR1 P2RY14 620/4885P2RY2 442/4885P2RY6 1484/4885
US-20020142980-A1 Nucleic acid molecules with novel chemical compositions capable of modulating gene expression NSUN2, RNMT, NSUN3 P2RY14 4652/4885P2RY2 4402/4885P2RY6 4071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.