Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17728698 | 1.00 | ALDH1A1 (0.33) | ALDH1A1ALOX15 | |
| SCHEMBL4610325 | 0.79 | ALOX15 (0.56) | ALDH1A1ALOX15 | |
| SCHEMBL30883778 | 0.79 | ALOX15 (0.56) | ALDH1A1ALOX15 | |
| SCHEMBL4610328 | 0.79 | ALOX15 (0.56) | ALDH1A1ALOX15 | |
| SCHEMBL9186021 | 0.76 | KMT2A (0.63) | ALDH1A1ALOX15 | |
| SCHEMBL21518307 | 0.74 | ALDH1A1 (0.37) | ALDH1A1ALOX15 | |
| SCHEMBL21518284 | 0.74 | ALDH1A1 (0.37) | ALDH1A1ALOX15 | |
| SCHEMBL21518289 | 0.74 | ALDH1A1 (0.37) | ALDH1A1ALOX15 | |
| SCHEMBL3390995 | 0.74 | — | — | |
| SCHEMBL26599107 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369827-A1 | POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES | Visolis, Inc. | 2020-11-26 | — | — | US | disclosed |
| WO-2016077555-A1 | POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES | Visolis, Inc. (US) | 2016-05-19 | — | — | WO | disclosed |
| US-20160130389-A1 | POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES | Visolis, Inc. | 2016-05-12 | — | — | US | disclosed |
| US-20160130389-A1 | POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES | Visolis, Inc. | 2016-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130389-A1 | POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES | COASY, FASN, GGPS1 | ALDH1A1 968/4885ALOX15 27/4885 |
| US-20200369827-A1 | POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES | COASY, FASN, GGPS1 | ALDH1A1 968/4885ALOX15 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.