Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 5/20 | 0.49 |
| ▸ | FNTB | P49356 | 3/20 | 0.49 |
| ▸ | SQLE | Q14534 | 4/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610325 | 1.00 | ALOX15 (0.56) | ALOX15ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL30883778 | 1.00 | ALOX15 (0.56) | ALOX15ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL356732 | 0.81 | KMT2A (0.62) | ALOX15ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL114886 | 0.81 | KMT2A (0.62) | ALOX15ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL114887 | 0.81 | KMT2A (0.62) | ALOX15ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL9186021 | 0.81 | KMT2A (0.63) | ALOX15ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL3390995 | 0.80 | — | — | |
| SCHEMBL226426 | 0.80 | ALDH1A1 (0.61) | ALOX15ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL1865864 | 0.80 | ALDH1A1 (0.61) | ALOX15ALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL226427 | 0.80 | ALDH1A1 (0.61) | ALOX15ALDH1A1KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294671-B1 | UTILISATION OF KETONES AS PRECURSORS OF ACTIVE COMPOUNDS | FIRMENICH & CIE (CH) | 2008-10-15 | — | — | EP | disclosed |
| US-6949680-B2 | Ketones as precursors of active compounds | FIRMENICH SA (CH) | 2005-09-27 | — | — | US | disclosed |
| US-20030129212-A1 | Ketones as precursors of active compounds | FIRMENICH SA (CH) | 2003-07-10 | — | — | US | disclosed |
| EP-1294671-A2 | UTILISATION OF KETONES AS PRECURSORS OF ACTIVE COMPOUNDS | FIRMENICH SA (CH) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096272-A2 | UTILISATION OF KETONES AS PRECURSORS OF ACTIVE COMPOUNDS | FIRMENICH SA (CH) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030129212-A1 | Ketones as precursors of active compounds | PKN3, PKM, FPR3 | ALOX15 563/4885ALDH1A1 828/4885KMT2A 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.