Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | F7 | P08709 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469781 | 0.88 | AHR (0.78) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL8187476 | 0.84 | AHR (0.70) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL566682 | 0.81 | AHR (0.56) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL30389969 | 0.81 | AHR (0.56) | AHRNR4A2CYP2A6F7LTA4H | |
| Tert-Butyl Formate SCHEMBL27752469 | 0.80 | CYP2A6 (0.46) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL9117926 | 0.78 | KDM4E (0.44) | AHRNR4A2CYP2A6USP2GAA | |
| SCHEMBL5850255 | 0.75 | NPC1 (0.79) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL2530865 | 0.73 | GPR84 (0.67) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL6017338 | 0.71 | AHR (0.56) | AHRNR4A2CYP2A6F7LTA4H | |
| SCHEMBL405311 | 0.71 | AHR (1.00) | AHRNR4A2CYP2A6F7LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120131638-A | Application of indole compound with electron withdrawing group in inhibiting plasmid conjugation transfer | 扬州大学 | 2025-06-13 | — | — | CN | claimed |
| CN-113943244-B | Sulfur-containing gamma, gamma-diindolylbutyramide compounds prepared by difunctional reactions | 温州大学 | 2023-05-23 | — | — | CN | claimed |
| CN-112574093-B | Novel green method for preparing 3-diaryl methyl substituted indole compound | 湖南理工学院 | 2022-10-04 | — | — | CN | claimed |
| CN-115057803-A | S- (methyl-d) 3 ) Synthetic method and application of phenylether substances | 杭州师范大学 | 2022-09-16 | — | — | CN | claimed |
| CN-112225684-B | Synthetic method of organic intermediate 5-iodoindole | 山东省农业科学院农产品研究所 | 2022-06-17 | — | — | CN | claimed |
| CN-113943244-A | Sulfur-containing gamma, gamma-diindolyl butyramide compound prepared by double-functionalization reaction | 温州大学 | 2022-01-18 | — | — | CN | claimed |
| CN-112574093-A | Novel green method for preparing 3-diaryl methyl substituted indole compound | 湖南理工学院 | 2021-03-30 | — | — | CN | claimed |
| CN-112479972-A | Synthesis method of 5-iodoindole compound | 西北大学 | 2021-03-12 | — | — | CN | claimed |
| CN-112225684-A | Synthetic method of organic intermediate 5-iodoindole | 山东省农业科学院农产品研究所 | 2021-01-15 | — | — | CN | claimed |
| CN-108017557-B | Cyanidation method for preparing nitrile compound | 中国科学院兰州化学物理研究所苏州研究院 | 2020-11-24 | — | — | CN | claimed |
| CN-111004283-A | Preparation method of 3-phosphoryl indole compound | 南京理工大学 | 2020-04-14 | — | — | CN | claimed |
| CN-107778210-B | Synthetic method of 3-selenoindole compound | 苏州大学 | 2020-04-10 | — | — | CN | claimed |
| CN-106117113-A | Polysubstituted carbazole, derivant and synthetic method thereof | 湘潭大学 | 2016-11-16 | — | — | CN | claimed |
| US-20260138948-A1 | N-SUBSTITUTED INDOLES AS 5-HYDROXYTRYPTAMINE (5-HT) SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS | TERRAN BIOSCIENCES INC (US) | 2026-05-21 | — | — | US | disclosed |
| EP-4720037-A1 | CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | 16380026 Canada Inc. (CA) | 2026-04-08 | — | — | EP | disclosed |
| EP-4720036-A1 | CYP26B1 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | 16380026 Canada Inc. (CA) | 2026-04-08 | — | — | EP | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1998046570-A1 | SUBSTITUTED HETEROAROMATIC 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1995034658-A1 | MICROBIAL PRODUCTION OF INDOLE-3-ACETIC ACIDS AND SUBSTITUTED ANALOGS THEREOF VIA FERMENTATION | GENENCOR INTERNATIONAL, INC. (US) | 1995-12-21 | — | — | WO | disclosed |
| WO-1995034657-A2 | MICROBIAL PRODUCTION OF 4-, 5-, 6- AND 7-SUBSTITUTED INDOLE AND TRYPTOPHAN ANALOGS VIA FERMENTATION | GENENCOR INTERNATIONAL, INC. (US) | 1995-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260138948-A1 | N-SUBSTITUTED INDOLES AS 5-HYDROXYTRYPTAMINE (5-HT) SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS | HTR1D, HTR2C, TPH1 | AHR 501/4885NR4A2 1825/4885CYP2A6 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.