SCHEMBL17733136

SCHEMBL17733136

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nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19980838 0.85 ALDH1A1 (0.41) ALDH1A1LMNATP53TSHR
SCHEMBL13776554 0.85 ALDH1A1 (0.41) ALDH1A1LMNATP53TSHR
SCHEMBL15120294 0.83 ALDH1A1 (0.39) ALDH1A1LMNA
SCHEMBL23638105 0.82 ALDH1A1 (0.35) ALDH1A1LMNA
SCHEMBL20013480 0.81 ALDH1A1 (0.38) ALDH1A1LMNATSHR
SCHEMBL13780422 0.78 ALDH1A1 (0.39) ALDH1A1LMNATSHR
SCHEMBL18559486 0.77 LMNA (0.38) ALDH1A1LMNATSHR
SCHEMBL12380353 0.76 ALDH1A1 (0.33) ALDH1A1
SCHEMBL313661 0.76
SCHEMBL2492911 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3018165-A1 POLYORGANOSILOXANE COMPOUND, METHOD FOR PREPARING SAME, AND COPOLYCARBONATE RESIN COMPRISING SAME LG Chem, Ltd. (KR) 2016-05-11 EP disclosed