SCHEMBL18559486

SCHEMBL18559486

C=C/C(O)=C\C=C(/C=C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
ALDH1A1 P00352 2/20 0.30
TSHR P16473 1/20 0.30
FGFR4 P22455 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19147718 0.83 LMNA (0.32) LMNA
SCHEMBL2492911 0.78
SCHEMBL313661 0.78
SCHEMBL19578524 0.78
SCHEMBL26414903 0.77 LMNA (0.36) LMNA
SCHEMBL26414869 0.77 ALDH1A1 (0.41) LMNAALDH1A1TSHRFGFR4
SCHEMBL17733136 0.77 ALDH1A1 (0.41) LMNAALDH1A1TSHR
SCHEMBL19980838 0.77 ALDH1A1 (0.41) LMNAALDH1A1TSHR
SCHEMBL20340973 0.76 LMNA (0.40) LMNAALDH1A1TSHR
SCHEMBL27468544 0.76 LMNA (0.40) LMNAALDH1A1TSHRFGFR4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10654307-B2 Rotogravure printing processes for producing optically variable security features SICPA HOLDING SA (CH) 2020-05-19 US disclosed
US-9816031-B2 Composite marking based on chiral liquid crystal precursors SICPA HOLDING SA (CH) 2017-11-14 US disclosed
US-9579922-B2 Marking comprising a printable code and a chiral liquid crystal polymer layer SICPA HOLDING SA (CH) 2017-02-28 US disclosed