Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205863 | 0.85 | HTR2A (0.32) | HTR2AHTR2CHTR2BHTR7MCL1 | |
| SCHEMBL27677971 | 0.81 | HTR7 (0.39) | HTR2AHTR2CHTR2BHTR7TYMS | |
| SCHEMBL29501037 | 0.75 | PARP10 (0.34) | — | |
| SCHEMBL9114452 | 0.75 | PARP10 (0.34) | — | |
| SCHEMBL25675742 | 0.72 | ANPEP (0.31) | — | |
| SCHEMBL29634842 | 0.71 | PNMT (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL31503035 | 0.71 | CA9 (0.35) | — | |
| SCHEMBL2524442 | 0.71 | — | — | |
| SCHEMBL30344009 | 0.71 | KDM1A (0.37) | HTR2AHTR2C | |
| SCHEMBL7650098 | 0.71 | CA9 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072864-A | TDO2 INHIBITORS | 基因泰克公司 | 2019-07-30 | — | — | CN | disclosed |
| EP-1696912-B1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2016-05-11 | — | — | EP | disclosed |