Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107546 | 0.80 | NAMPT (0.33) | NAMPTPOLBMAPTHSD17B10GAA | |
| SCHEMBL17733614 | 0.80 | L3MBTL1 (0.33) | NAMPTPOLBMAPTHSD17B10GAA | |
| SCHEMBL23747568 | 0.75 | NAMPT (0.30) | NAMPT | |
| SCHEMBL19983385 | 0.69 | NAMPT (0.32) | NAMPT | |
| SCHEMBL24302594 | 0.68 | SMN1; SMN2 (0.33) | NAMPTMAPTHSD17B10GAAPKM | |
| SCHEMBL23640361 | 0.68 | SMN1; SMN2 (0.33) | NAMPTMAPTHSD17B10GAAPKM | |
| SCHEMBL7874522 | 0.67 | HSP90AA1 (0.33) | NAMPTGAAHSP90AA1HSP90AB1 | |
| SCHEMBL5960697 | 0.66 | SMN1; SMN2 (0.34) | NAMPTPOLBMAPTHSD17B10GAA | |
| SCHEMBL17733547 | 0.66 | NAMPT (0.33) | NAMPTMAPTHSD17B10GAAPKM | |
| SCHEMBL13591827 | 0.64 | HSP90AA1 (0.33) | NAMPTHSD17B10GAAPKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696912-B1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2016-05-11 | — | — | EP | disclosed |