Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17734824 | 0.95 | KDM4E (0.34) | CRHR1KDM4ETYMSCA12CA1 | |
| SCHEMBL17734581 | 0.95 | CRHR1 (0.36) | CRHR1KDM4ETYMSCA12CA1 | |
| SCHEMBL17734819 | 0.92 | TYMS (0.37) | CRHR1KDM4ETYMSCA12CA1 | |
| SCHEMBL17734838 | 0.92 | TYMS (0.37) | CRHR1KDM4ETYMSCA12CA1 | |
| SCHEMBL17734827 | 0.91 | TYMS (0.36) | CRHR1KDM4ETYMSCA12CA1 | |
| SCHEMBL17734815 | 0.90 | TYMS (0.37) | CRHR1KDM4ETYMSCA12CA1 | |
| SCHEMBL17734577 | 0.90 | HSD17B1 (0.31) | CA12CA1CA2CA9TNKS2 | |
| SCHEMBL17734853 | 0.90 | CA12 (0.35) | CRHR1KDM4ETYMSCA12CA1 | |
| SCHEMBL17734843 | 0.89 | CA12 (0.41) | CRHR1CA12CA1CA2CA9 | |
| SCHEMBL17734813 | 0.89 | HPRT1 (0.36) | CRHR1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160133847-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2016-05-12 | — | — | US | disclosed |
| US-20160133847-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2016-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160133847-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | ARL1, CCNL2, APOL1 | CRHR1 1895/4885KDM4E 1331/4885TYMS 4657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.