Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19560628 | 0.94 | ALDH1A1 (0.44) | ALDH1A1CASP2NAAANAMPTLMNA | |
| SCHEMBL16300423 | 0.88 | CASP2 (0.41) | ALDH1A1CASP2NAAANAMPTLMNA | |
| SCHEMBL19663172 | 0.84 | LMNA (0.49) | ALDH1A1NAMPTLMNAPKMCNR2 | |
| SCHEMBL21754688 | 0.81 | CNR2 (0.36) | ALDH1A1CASP2NAAANAMPTLMNA | |
| SCHEMBL17122488 | 0.81 | CASP2 (0.56) | CASP2NAAAFAAHEPHX1 | |
| SCHEMBL22851659 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CASP2NAAANAMPTLMNA | |
| SCHEMBL18768756 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CASP2NAAANAMPTLMNA | |
| SCHEMBL16689691 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CASP2NAAANAMPTLMNA | |
| SCHEMBL17881973 | 0.80 | CASP2 (0.42) | CASP2NAAAHPSEFAAH | |
| SCHEMBL29552353 | 0.80 | PRMT1 (0.43) | ALDH1A1CASP2NAAALMNAHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247504-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | Life Technologies Corporation | 2017-08-31 | — | — | US | disclosed |
| WO-2016073052-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | Life Technologies Corporation (US) | 2016-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247504-A1 | DIBENZOSILOLE MONOMERS AND POLYMERS AND METHODS FOR THEIR PREPARATION AND USE | DDOST, DDT, DAD1 | ALDH1A1 2442/4885CASP2 4631/4885NAAA 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.