SCHEMBL17744861

SCHEMBL17744861

Nc1ccccc1-c1c(N)cccc1OC(=O)c1ccc(C(=O)Oc2cccc(N)c2-c2ccccc2N)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 1/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.46
▸ TSHR P16473 1/20 0.46
▸ KMT2A Q03164 5/20 0.45
▸ MAPT P10636 2/20 0.45
▸ SLC6A3 Q01959 1/20 0.44
▸ PTGES O14684 1/20 0.43
▸ ESR1 P03372 3/20 0.43
▸ ESR2 Q92731 3/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ JAK2 O60674 1/20 0.43
▸ USP2 O75604 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ PRSS1 P07477 3/20 0.42
▸ ACR P10323 3/20 0.42
▸ LMNA P02545 2/20 0.40
▸ SERPINE1 P05121 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17744863 0.94 TOP1 (0.52) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL17744831 0.91 TOP1 (0.51) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL17744773 0.87 HSD17B10 (0.44) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL17744832 0.86 TOP1 (0.50) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL3794675 0.82 PTGS2 (0.46) SMN1; SMN2TSHRKMT2AMAPTESR1
SCHEMBL17744774 0.82 HSD17B10 (0.50) TOP1TSHRKMT2AMAPTSLC6A3
SCHEMBL13292717 0.81 SMN1; SMN2 (0.63) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL30335393 0.80 KMT2A (0.56) TOP1SMN1; SMN2TSHRKMT2AMAPT
SCHEMBL9337991 0.80 TOP1 (0.59) TOP1SMN1; SMN2KMT2AMAPTSLC6A3
SCHEMBL17744885 0.78 SLC6A3 (0.46) TOP1SMN1; SMN2TSHRKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 — — US disclosed
CN-105392838-B Composition epoxy resin, prepreg and carbon fibre reinforced composite 东丽株式会社 2018-12-14 — — CN disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 — — EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 — — US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 — — EP disclosed
CN-105392838-A Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES 2016-03-09 — — CN disclosed
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