SCHEMBL17744863

SCHEMBL17744863

Nc1ccccc1-c1c(N)cccc1OC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 1/20 0.52
▸ KMT2A Q03164 6/20 0.44
▸ SMN1; SMN2 Q16637 4/20 0.44
▸ MAPT P10636 3/20 0.44
▸ SLC6A3 Q01959 1/20 0.43
▸ RXRA P19793 2/20 0.43
▸ RXRB P28702 2/20 0.43
▸ RXRG P48443 2/20 0.43
▸ PTGES O14684 1/20 0.43
▸ MEN1 O00255 2/20 0.42
▸ USP2 O75604 2/20 0.42
▸ ESR1 P03372 2/20 0.42
▸ ESR2 Q92731 2/20 0.42
▸ HSD17B10 Q99714 2/20 0.42
▸ JAK2 O60674 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42
▸ TSHR P16473 1/20 0.42
▸ TTR P02766 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17744861 0.94 TOP1 (0.54) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL17744832 0.89 TOP1 (0.50) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL17744831 0.85 TOP1 (0.51) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL17744774 0.83 HSD17B10 (0.50) TOP1KMT2AMAPTSLC6A3ESR1
SCHEMBL17744773 0.82 HSD17B10 (0.44) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL31536329 0.82 SMN1; SMN2 (0.47) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL17744885 0.79 SLC6A3 (0.46) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL30335393 0.79 KMT2A (0.56) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL17744874 0.78 KMT2A (0.41) TOP1KMT2ASMN1; SMN2MAPTSLC6A3
SCHEMBL10782892 0.78 MAPT (0.62) TOP1KMT2ASMN1; SMN2MAPTSLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 — — US disclosed
CN-105392838-B Composition epoxy resin, prepreg and carbon fibre reinforced composite 东丽株式会社 2018-12-14 — — CN disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 — — EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 — — US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 — — EP disclosed
CN-105392838-A Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES 2016-03-09 — — CN disclosed
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