SCHEMBL17744848

SCHEMBL17744848

Nc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccc2N)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.75
FADS1 O60427 3/20 0.69
P2RX1 P51575 1/20 0.63
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
TDP1 Q9NUW8 2/20 0.60
NPC1 O15118 5/20 0.57
RAB9A P51151 5/20 0.57
ALDH1A1 P00352 3/20 0.57
LMNA P02545 3/20 0.56
KDM4E B2RXH2 3/20 0.55
HSD17B10 Q99714 2/20 0.55
HPGD P15428 2/20 0.55
TP53 P04637 1/20 0.55
HTT P42858 1/20 0.55
PRKCI P41743 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
GAA P10253 1/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2127535 0.94 PTGS1 (0.69) PTGS1FADS1P2RX1MEN1KMT2A
SCHEMBL30830441 0.94 PTGS1 (0.69) PTGS1FADS1P2RX1MEN1KMT2A
SCHEMBL1140055 0.94 PTGS1 (0.68) PTGS1FADS1P2RX1MEN1KMT2A
SCHEMBL4954215 0.93 PTGS1 (0.67) PTGS1FADS1P2RX1MEN1KMT2A
SCHEMBL4957349 0.93 LMNA (0.69) PTGS1FADS1P2RX1MEN1KMT2A
SCHEMBL15361168 0.91 SMN1; SMN2 (0.68) PTGS1FADS1P2RX1MEN1KMT2A
SCHEMBL5853941 0.91 PTGS1 (0.65) PTGS1FADS1P2RX1MEN1KMT2A
SCHEMBL1961876 0.91 NPC1 (0.68) PTGS1FADS1P2RX1MEN1KMT2A
SCHEMBL1961988 0.91 FADS1 (0.73) PTGS1FADS1P2RX1MEN1KMT2A
SCHEMBL30941935 0.91 LMNA (0.70) PTGS1FADS1P2RX1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
CN-105392838-B Composition epoxy resin, prepreg and carbon fibre reinforced composite 东丽株式会社 2018-12-14 CN disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed