Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | MAOB | P27338 | 4/20 | 0.70 |
| ▸ | GAA | P10253 | 4/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | GLA | P06280 | 3/20 | 0.70 |
| ▸ | CA2 | P00918 | 2/20 | 0.70 |
| ▸ | CA12 | O43570 | 1/20 | 0.70 |
| ▸ | CA3 | P07451 | 1/20 | 0.70 |
| ▸ | CA4 | P22748 | 1/20 | 0.70 |
| ▸ | CA6 | P23280 | 1/20 | 0.70 |
| ▸ | CA7 | P43166 | 1/20 | 0.70 |
| ▸ | CA9 | Q16790 | 1/20 | 0.70 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL648621 | 0.89 | MAOB (0.70) | HPGDKDM4EMAOBGAAALDH1A1 | |
| SCHEMBL4450673 | 0.85 | KDM4E (0.67) | HPGDKDM4EMAOBGAAALDH1A1 | |
| SCHEMBL13740830 | 0.85 | CA12 (0.57) | HPGDKDM4EMAOBGAAALDH1A1 | |
| SCHEMBL18591925 | 0.85 | CA12 (0.57) | HPGDKDM4EMAOBGAAALDH1A1 | |
| SCHEMBL3626320 | 0.84 | PTGS2 (0.58) | HPGDKDM4EMAOBGAAALDH1A1 | |
| SCHEMBL28044290 | 0.84 | CYP1A2 (0.57) | HPGDKDM4EMAOBGAAALDH1A1 | |
| SCHEMBL2246104 | 0.84 | MAPT (0.51) | HPGDKDM4EMAOBGAAALDH1A1 | |
| SCHEMBL29233648 | 0.83 | KDM4E (0.61) | HPGDKDM4EMAOBGAAALDH1A1 | |
| SCHEMBL742193 | 0.82 | MIF (0.68) | HPGDKDM4EMAOBGAAALDH1A1 | |
| SCHEMBL28367859 | 0.82 | CYP1A2 (0.50) | HPGDKDM4EMAOBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | NORTHEAST NORMAL UNIVERSITY (CN) | 2020-07-28 | — | — | US | claimed |
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | NORTHEAST NORMAL UNIVERSITY (CN) | 2018-07-12 | — | — | US | claimed |
| CN-102997991-A | Ultraviolet detection device | LIYANG PRODUCTIVITY PROMOTION CT | 2013-03-27 | — | — | CN | claimed |
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | NORTHEAST NORMAL UNIVERSITY (CN) | 2020-07-28 | — | — | US | disclosed |
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | NORTHEAST NORMAL UNIVERSITY (CN) | 2018-07-12 | — | — | US | disclosed |
| US-9707205-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2017-07-18 | — | — | US | disclosed |
| EP-2344484-B1 | S1P RECEPTORS MODULATORS AND USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2016-06-08 | — | — | EP | disclosed |
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD. (AU) | 2016-02-11 | — | — | US | disclosed |
| US-9193716-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2015-11-24 | — | — | US | disclosed |
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| US-20150065494-A1 | AMINOSTYRYLBENZOFURAN DERIVATIVES AS INHIBITORS AGAINST BETA-AMYLOID FIBRIL FORMATION, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-03-05 | — | — | US | disclosed |
| WO-2012068702-A1 | BENZO 5-MEMBERED UNSATURATED HETEROCYCLIC COMPOUNDS AND PREPARATION METHODS THEREOF | 中国医学科学院医药生物技术研究所 (CN) | 2012-05-31 | — | — | WO | disclosed |
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
| US-20110318388-A1 | S1P Receptors Modulators and Their Use Thereof | AKAAL PHARMA PTY LTD (AU) | 2011-12-29 | — | — | US | disclosed |
| EP-2344484-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| EP-2344446-A1 | S1P RECEPTORS MODULATORS | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010043000-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
| US-7015246-B2 | Benzofuran derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2006-03-21 | — | — | US | disclosed |
| US-20040220415-A1 | Benzofuran derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180195039-A1 | APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS | XPA, MEP1A, EED | HPGD 2257/4885KDM4E 280/4885MAOB 4107/4885 |
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | S1PR1, S1PR5, S1PR2 | HPGD 2567/4885KDM4E 1508/4885MAOB 3603/4885 |
| US-10723998-B2 | Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells | XPA, MEP1A, EED | HPGD 2257/4885KDM4E 280/4885MAOB 4107/4885 |
| US-20150065494-A1 | AMINOSTYRYLBENZOFURAN DERIVATIVES AS INHIBITORS AGAINST BETA-AMYLOID FIBRIL FORMATION, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | APP, BACE1, APBA1 | HPGD 2417/4885KDM4E 2665/4885MAOB 264/4885 |
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | HPGD 2115/4885KDM4E 1701/4885MAOB 4070/4885 |
| US-20040220415-A1 | Benzofuran derivatives | BPTF, ABCG2, ABCB1 | HPGD 534/4885KDM4E 1659/4885MAOB 575/4885 |
| US-20110318388-A1 | S1P Receptors Modulators and Their Use Thereof | S1PR1, S1PR5, S1PR2 | HPGD 2567/4885KDM4E 1508/4885MAOB 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.